Biomaterial Database

Surgical Control of a Primary Hepatic Carcinoid Tumor: A Case Report. 2009

Norio Yokoigawa, and Hiroaki Kitade, and Masaharu Ohishi, and Takashi Ozaki, and Takeshi Miyaso, and Satoshi Okazaki, and Koji Nakai, and Ryo Yoshida, and Seiki Imada, and Atsushi Imamura, and Yusai Kawaguchi, and Hideho Takada, and Nobuaki Shikata, and Toshihito Seki, and A-H Kwon

Departments of Surgery, Kansai Medical University, Osaka, Japan.

We report a primary hepatic carcinoid tumor occurring in a 47-year-old man. The patient consulted our hospital complaining of epigastralgia. Abdominal ultrasonography, computed tomography scanning, and magnetic resonance imaging showed a large mass in the right lobe of the liver. FDG-PET revealed 18F-FDG uptake by the right hepatic lobe. The tumor was a solid mass with cystic components, approximately 15 cm in diameter. We conducted an extended right lobectomy of the liver. The resected specimen was a solid tumor with cystic components and hemorrhagic lesion. Microscopic findings showed that the tumor cells had round nuclei and formed trabecular patterns. Immunohistologically, tumor cells were stained positive for chromogranin A, neuron specific enolase, CD56, and S-100. Careful examinations before and after the operation revealed no other possible origin of the tumor. Based on these findings, the tumor was diagnosed as a primary hepatic carcinoid. This is a report of a rare case of a primary hepatic carcinoid tumor with a discussion of several other relevant reports.