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Acanthamoeba meningoencephalitis in an immunocompetent patient: an autopsy case report. 2011

Rajesh Reddy, and Mudumba Vijayasaradhi, and Megha S Uppin, and Sundaram Challa, and Afshan Jabeen, and Rupam Borghain
Department of Neurosurgery, Nizam's Institute of Medical Sciences, Hyderabad, India.

Chronic granulomatous CNS infections may be caused by tuberculosis, fungi and rarely by free-living amoeba, especially in immunocompromised individuals. We report a rare, fatal case of granulomatous amoebic encephalitis in an immunocompetent patient mimicking CNS tuberculosis, and review the imageological features and diagnostic tests.

UI MeSH Term Description Entries
D008297 Male Males
D003937 Diagnosis, Differential Determination of which one of two or more diseases or conditions a patient is suffering from by systematically comparing and contrasting results of diagnostic measures. Diagnoses, Differential,Differential Diagnoses,Differential Diagnosis
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000048 Acanthamoeba A genus of free-living soil amoebae that produces no flagellate stage. Its organisms are pathogens for several infections in humans and have been found in the eye, bone, brain, and respiratory tract. Acanthamoebas
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000562 Amebiasis Infection with any of various amebae. It is an asymptomatic carrier state in most individuals, but diseases ranging from chronic, mild diarrhea to fulminant dysentery may occur. Abscess, Amebic,Acanthamebiasis,Ameboma,Amoebiasis,Iodamoebiasis,Acanthamoeba Infection,Balamuthia Infection,Abscesses, Amebic,Acanthamebiases,Acanthamoeba Infections,Amebiases,Amebic Abscess,Amebic Abscesses,Amoebiases,Balamuthia Infections,Infection, Acanthamoeba,Infection, Balamuthia,Iodamoebiases
D001344 Autopsy Postmortem examination of the body. Autopsies,Post-Mortem Examination,Postmortem Examination,Examination, Post-Mortem,Examination, Postmortem,Examinations, Post-Mortem,Examinations, Postmortem,Post Mortem Examination,Post-Mortem Examinations,Postmortem Examinations
D017809 Fatal Outcome Death resulting from the presence of a disease in an individual, as shown by a single case report or a limited number of patients. This should be differentiated from DEATH, the physiological cessation of life and from MORTALITY, an epidemiological or statistical concept. Fatal Outcomes,Outcome, Fatal,Outcomes, Fatal
D020306 Tuberculosis, Central Nervous System Tuberculosis of the brain, spinal cord, or meninges (TUBERCULOSIS, MENINGEAL), most often caused by MYCOBACTERIUM TUBERCULOSIS and rarely by MYCOBACTERIUM BOVIS. The infection may be limited to the nervous system or coexist in other organs (e.g., TUBERCULOSIS, PULMONARY). The organism tends to seed the meninges causing a diffuse meningitis and leads to the formation of TUBERCULOMA, which may occur within the brain, spinal cord, or perimeningeal spaces. Tuberculous involvement of the vertebral column (TUBERCULOSIS, SPINAL) may result in nerve root or spinal cord compression. (From Adams et al., Principles of Neurology, 6th ed, pp717-20) Central Nervous System Tuberculosis
D020808 Central Nervous System Protozoal Infections Infections of the brain, spinal cord, or meninges by single celled organisms of the former subkingdom known as protozoa. The central nervous system may be the primary or secondary site of protozoal infection. These diseases may occur as OPPORTUNISTIC INFECTIONS or arise in immunocompetent hosts. CNS Protozoal Infections,Cerebral Protozoal Infections,Meningoencephalitis, Protozoal,Protozoal Infections, Central Nervous System,Acanthamoeba Meningoencephalitis,Amebic Meningoencephalitis,Balamuthia mandrillaris CNS Infection,Balamuthia mandrillaris Meningoencephalitis,Infection, Central Nervous System, Protozoal,Infections, Protozoal, Central Nervous System,Naegleria fowleri Infection,Naegleria fowleri Meningoencephalitis,Primary Amebic Meningoencephalitis,Protozoal Infections, Cerebral,Protozoal Meningoencephalitis,Sappinia diploidea Meningoencephalitis,Acanthamoeba Meningoencephalitides,Amebic Meningoencephalitides,Amebic Meningoencephalitides, Primary,Amebic Meningoencephalitis, Primary,Balamuthia mandrillaris Meningoencephalitides,CNS Protozoal Infection,Cerebral Protozoal Infection,Infection, CNS Protozoal,Infection, Cerebral Protozoal,Infection, Naegleria fowleri,Infections, CNS Protozoal,Meningoencephalitides, Acanthamoeba,Meningoencephalitides, Amebic,Meningoencephalitides, Balamuthia mandrillaris,Meningoencephalitides, Naegleria fowleri,Meningoencephalitides, Primary Amebic,Meningoencephalitides, Protozoal,Meningoencephalitides, Sappinia diploidea,Meningoencephalitis, Acanthamoeba,Meningoencephalitis, Amebic,Meningoencephalitis, Balamuthia mandrillaris,Meningoencephalitis, Naegleria fowleri,Meningoencephalitis, Primary Amebic,Meningoencephalitis, Sappinia diploidea,Naegleria fowleri Infections,Naegleria fowleri Meningoencephalitides,Primary Amebic Meningoencephalitides,Protozoal Infection, CNS,Protozoal Infection, Cerebral,Protozoal Infections, CNS,Protozoal Meningoencephalitides,Sappinia diploidea Meningoencephalitides

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