-transparent.png){kind=logo}
Clinical features and microbiologic data on all cases of serious (hospitalized) Group A streptococcal infections in children managed at our institution between 1985 and 1988 are presented. All 6 cases were caused by toxin-producing strains. Four of 6 were toxin A-producing strains whereas none of 58 community-acquired (Group A streptococcal) pharyngeal isolates in the same period was a toxin A producer. A review of the literature on the incidence of toxin A-producing strains provides information suggesting a resurgence of such strains in the late 1980s after a relative disappearance of toxin B production in isolates from these patients was also significantly greater than in the isolates acquired from the community in uncomplicated pharyngitis. These findings suggest a role for exotoxin in severe manifestations of Group A streptococcal disease in children.
K Belani, and
P M Schlievert, and
E L Kaplan, and
P Ferrieri
November 1979,
The Journal of infectious diseases,
K Belani, and
P M Schlievert, and
E L Kaplan, and
P Ferrieri
November 1994,
FEMS immunology and medical microbiology,
K Belani, and
P M Schlievert, and
E L Kaplan, and
P Ferrieri
April 2006,
Journal of Korean medical science,
K Belani, and
P M Schlievert, and
E L Kaplan, and
P Ferrieri
January 1991,
Current topics in microbiology and immunology,
K Belani, and
P M Schlievert, and
E L Kaplan, and
P Ferrieri
December 1981,
Infection and immunity,
K Belani, and
P M Schlievert, and
E L Kaplan, and
P Ferrieri
January 1997,
Advances in experimental medicine and biology,
K Belani, and
P M Schlievert, and
E L Kaplan, and
P Ferrieri
December 1991,
The Journal of infectious diseases,
K Belani, and
P M Schlievert, and
E L Kaplan, and
P Ferrieri
February 2003,
FEMS microbiology letters,
K Belani, and
P M Schlievert, and
E L Kaplan, and
P Ferrieri
March 1999,
The Journal of infectious diseases,
K Belani, and
P M Schlievert, and
E L Kaplan, and
P Ferrieri
April 2008,
The Journal of infection,
