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Altogether 35 children suffering from different forms of glomerulonephritis were examined. It has been shown that in the pathogenesis of glomerulonephritis in children, an appreciable role is played not only by the action of pathogenic immune complexes but also by the mechanism of antibody-dependent cytotoxicity due to K-cells and lymphocytotoxicity, influencing the regulatory subpopulations of immunocompetent cells and acting directly on the structures of renal tissue. The nephrotic syndrome is characterized by the enhancement of serum lymphocytotoxicity whereas the nephritic syndrome by a rise in the blood of circulating immune complexes. In view of the fact that the process may become chronic, the rise of the activity of K-cells, of the level of lymphocytotoxins and the absence from the serum of circulating immune complexes should be regarded as unfavourable prognostic criteria.
E I Shefatova, and
B N Sofronov, and
L S Kositskaia, and
K M Sergeeva
January 1981,
Terapevticheskii arkhiv,
E I Shefatova, and
B N Sofronov, and
L S Kositskaia, and
K M Sergeeva
June 1984,
Pediatriia,
E I Shefatova, and
B N Sofronov, and
L S Kositskaia, and
K M Sergeeva
December 1977,
Pediatriia akusherstvo i ginekologiia,
E I Shefatova, and
B N Sofronov, and
L S Kositskaia, and
K M Sergeeva
August 1985,
Pediatriia,
E I Shefatova, and
B N Sofronov, and
L S Kositskaia, and
K M Sergeeva
September 1980,
Voprosy okhrany materinstva i detstva,
E I Shefatova, and
B N Sofronov, and
L S Kositskaia, and
K M Sergeeva
January 1980,
Minerva nefrologica,
E I Shefatova, and
B N Sofronov, and
L S Kositskaia, and
K M Sergeeva
October 1980,
Pediatriia,
E I Shefatova, and
B N Sofronov, and
L S Kositskaia, and
K M Sergeeva
January 1987,
Vestnik dermatologii i venerologii,
E I Shefatova, and
B N Sofronov, and
L S Kositskaia, and
K M Sergeeva
January 1982,
Voprosy onkologii,
E I Shefatova, and
B N Sofronov, and
L S Kositskaia, and
K M Sergeeva
April 1980,
Ortopediia travmatologiia i protezirovanie,
