Medium conditioned by human neuroblastoma BE(2)-C cells contains an autocrine/paracrine acting growth factor with properties similar to insulin-like growth factor II. 1991

O M el-Badry, and M B Meyers, and B A Spengler, and T D Chang, and R A Ross, and J L Biedler
Laboratory of Cellular and Biochemical Genetics, Memorial Sloan-Kettering Cancer Center, New York, NY 10021.

UI MeSH Term Description Entries
D007335 Insulin-Like Growth Factor II A well-characterized neutral peptide believed to be secreted by the LIVER and to circulate in the BLOOD. It has growth-regulating, insulin-like and mitogenic activities. The growth factor has a major, but not absolute, dependence on SOMATOTROPIN. It is believed to be a major fetal growth factor in contrast to INSULIN-LIKE GROWTH FACTOR I, which is a major growth factor in adults. IGF-II,Multiplication-Stimulating Activity,Somatomedin MSA,IGF-2,Insulin Like Growth Factor II,Insulin-Like Somatomedin Peptide II,Multiplication-Stimulating Factor,Somatomedin A,Factor, Multiplication-Stimulating,Insulin Like Somatomedin Peptide II,Multiplication Stimulating Activity,Multiplication Stimulating Factor
D007525 Isoelectric Focusing Electrophoresis in which a pH gradient is established in a gel medium and proteins migrate until they reach the site (or focus) at which the pH is equal to their isoelectric point. Electrofocusing,Focusing, Isoelectric
D008970 Molecular Weight The sum of the weight of all the atoms in a molecule. Molecular Weights,Weight, Molecular,Weights, Molecular
D009447 Neuroblastoma A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51) Neuroblastomas
D002449 Cell Aggregation The phenomenon by which dissociated cells intermixed in vitro tend to group themselves with cells of their own type. Aggregation, Cell,Aggregations, Cell,Cell Aggregations
D002455 Cell Division The fission of a CELL. It includes CYTOKINESIS, when the CYTOPLASM of a cell is divided, and CELL NUCLEUS DIVISION. M Phase,Cell Division Phase,Cell Divisions,Division Phase, Cell,Division, Cell,Divisions, Cell,M Phases,Phase, Cell Division,Phase, M,Phases, M
D002460 Cell Line Established cell cultures that have the potential to propagate indefinitely. Cell Lines,Line, Cell,Lines, Cell
D002850 Chromatography, Gel Chromatography on non-ionic gels without regard to the mechanism of solute discrimination. Chromatography, Exclusion,Chromatography, Gel Permeation,Chromatography, Molecular Sieve,Gel Filtration,Gel Filtration Chromatography,Chromatography, Size Exclusion,Exclusion Chromatography,Gel Chromatography,Gel Permeation Chromatography,Molecular Sieve Chromatography,Chromatography, Gel Filtration,Exclusion Chromatography, Size,Filtration Chromatography, Gel,Filtration, Gel,Sieve Chromatography, Molecular,Size Exclusion Chromatography
D003470 Culture Media Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN. Media, Culture
D004220 Disulfides Chemical groups containing the covalent disulfide bonds -S-S-. The sulfur atoms can be bound to inorganic or organic moieties. Disulfide

Related Publications

O M el-Badry, and M B Meyers, and B A Spengler, and T D Chang, and R A Ross, and J L Biedler
November 1995, Experimental cell research,
O M el-Badry, and M B Meyers, and B A Spengler, and T D Chang, and R A Ross, and J L Biedler
November 1989, Molecular endocrinology (Baltimore, Md.),
O M el-Badry, and M B Meyers, and B A Spengler, and T D Chang, and R A Ross, and J L Biedler
January 1997, Brain research,
O M el-Badry, and M B Meyers, and B A Spengler, and T D Chang, and R A Ross, and J L Biedler
January 1991, Acta paediatrica Scandinavica. Supplement,
O M el-Badry, and M B Meyers, and B A Spengler, and T D Chang, and R A Ross, and J L Biedler
July 1996, The Journal of clinical endocrinology and metabolism,
O M el-Badry, and M B Meyers, and B A Spengler, and T D Chang, and R A Ross, and J L Biedler
October 1998, Experimental cell research,
O M el-Badry, and M B Meyers, and B A Spengler, and T D Chang, and R A Ross, and J L Biedler
March 2004, Cancer letters,
O M el-Badry, and M B Meyers, and B A Spengler, and T D Chang, and R A Ross, and J L Biedler
October 1998, Scandinavian journal of gastroenterology,
O M el-Badry, and M B Meyers, and B A Spengler, and T D Chang, and R A Ross, and J L Biedler
February 1991, The Journal of clinical investigation,
O M el-Badry, and M B Meyers, and B A Spengler, and T D Chang, and R A Ross, and J L Biedler
January 1991, Progress in clinical and biological research,
Copied contents to your clipboard!