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Metastatic breast cancer presenting as a primary hindgut neuroendocrine tumour. 2010
Alicia F C Okines, and
Eliza A Hawkes, and
Sheela Rao, and
Nicholas VAN As, and
Henry Marsh, and
Angela Riddell, and
Philip O G Wilson, and
Peter Osin, and
Andrew C Wotherspoon, and
Andrew C Wetherspoon
Department of Medicine, Royal Marsden Hospital, Downs Road, Sutton, Surrey, SM2 5PT, U.K.
The examination of limited, potentially non-representative fragments of tumour tissue from a core biopsy can be misleading and misdirect subsequent treatment, especially in cases where a primary tumour has not been identified. This case report is of a 65-year-old woman presenting with a destructive sacral mass, diagnosed on radiological imaging and core biopsy as a hindgut neuroendocrine tumour, which on histopathological review of the subsequently resected tumour was found instead to represent a metastasis from an occult hormone-positive breast cancer with neuroendocrine features.
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