The aim of this study was to analyze the relationship of levels of self esteem and alcohol consumption in adolescents, by carrying out a transversal, descriptive study, in a college of nursing of Queretaro in Mexico, in the month of July 2008, with a sample of 109 adolescents, between 17 and 20 years old. For attainment of the data two instruments were applied: AUDIT and the Rosemberg self esteem scale. The majority of the participating adolescents had high self esteem (94.5%) and none presented low self esteem. Of the adolescents in the study 80.7% did not consume alcohol hazardously. It was concluded that the adolescents presented high self esteem and low alcohol consumption. Therefore, it is necessary to implement preventive programs related to alcohol consumption and to identify the protective factors to guarantee the maintenance of healthy habits for the adolescents.