-transparent.png){kind=logo}
Actin filament length tunes elasticity of flexibly cross-linked actin networks. 2010
K E Kasza, and
C P Broedersz, and
G H Koenderink, and
Y C Lin, and
W Messner, and
E A Millman, and
F Nakamura, and
T P Stossel, and
F C Mackintosh, and
D A Weitz
School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts, USA.
Networks of the cytoskeletal biopolymer actin cross-linked by the compliant protein filamin form soft gels that stiffen dramatically under shear stress. We demonstrate that the elasticity of these networks shows a strong dependence on the mean length of the actin polymers, unlike networks with small, rigid cross-links. This behavior is in agreement with a model of rigid filaments connected by multiple flexible linkers.
Related Publications
K E Kasza, and
C P Broedersz, and
G H Koenderink, and
Y C Lin, and
W Messner, and
E A Millman, and
F Nakamura, and
T P Stossel, and
F C Mackintosh, and
D A Weitz
June 2021,
Soft matter,
K E Kasza, and
C P Broedersz, and
G H Koenderink, and
Y C Lin, and
W Messner, and
E A Millman, and
F Nakamura, and
T P Stossel, and
F C Mackintosh, and
D A Weitz
February 2012,
Physical review letters,
K E Kasza, and
C P Broedersz, and
G H Koenderink, and
Y C Lin, and
W Messner, and
E A Millman, and
F Nakamura, and
T P Stossel, and
F C Mackintosh, and
D A Weitz
April 2013,
Physical review. E, Statistical, nonlinear, and soft matter physics,
K E Kasza, and
C P Broedersz, and
G H Koenderink, and
Y C Lin, and
W Messner, and
E A Millman, and
F Nakamura, and
T P Stossel, and
F C Mackintosh, and
D A Weitz
November 1985,
The Journal of cell biology,
K E Kasza, and
C P Broedersz, and
G H Koenderink, and
Y C Lin, and
W Messner, and
E A Millman, and
F Nakamura, and
T P Stossel, and
F C Mackintosh, and
D A Weitz
September 2001,
Biophysical journal,
K E Kasza, and
C P Broedersz, and
G H Koenderink, and
Y C Lin, and
W Messner, and
E A Millman, and
F Nakamura, and
T P Stossel, and
F C Mackintosh, and
D A Weitz
March 2011,
Physical review. E, Statistical, nonlinear, and soft matter physics,
K E Kasza, and
C P Broedersz, and
G H Koenderink, and
Y C Lin, and
W Messner, and
E A Millman, and
F Nakamura, and
T P Stossel, and
F C Mackintosh, and
D A Weitz
January 2001,
Results and problems in cell differentiation,
K E Kasza, and
C P Broedersz, and
G H Koenderink, and
Y C Lin, and
W Messner, and
E A Millman, and
F Nakamura, and
T P Stossel, and
F C Mackintosh, and
D A Weitz
April 2018,
Physical review letters,
K E Kasza, and
C P Broedersz, and
G H Koenderink, and
Y C Lin, and
W Messner, and
E A Millman, and
F Nakamura, and
T P Stossel, and
F C Mackintosh, and
D A Weitz
February 2007,
Physical review letters,
K E Kasza, and
C P Broedersz, and
G H Koenderink, and
Y C Lin, and
W Messner, and
E A Millman, and
F Nakamura, and
T P Stossel, and
F C Mackintosh, and
D A Weitz
August 2016,
Soft matter,
