BIOMAT Database Logo BIOMAT Database Logo

Prediction of osteoconductive activity of modified potassium fluorrichterite glass-ceramics by immersion in simulated body fluid. 2010

Shashwat Bhakta, and Deepak K Pattanayak, and Hiroaki Takadama, and Tadashi Kokubo, and Cheryl A Miller, and Mehdi Mirsaneh, and Ian M Reaney, and Ian Brook, and Richard van Noort, and Paul V Hatton
Centre for Biomaterials and Tissue Engineering, School of Clinical Dentistry, University of Sheffield, Claremont Crescent, Sheffield S10 2TA, UK. Shashwat.bhakta@sth.nhs.uk

Potassium fluorrichterite (KNaCaMg(5)Si(8)O(22)F(2)) glass-ceramics were modified by either increasing the concentration of calcium (GC5) or by the addition of P(2)O(5) (GP2). The stoichiometric composition (GST), GC5 and GP2 were soaked in simulated body fluid (SBF) along with 45S5-type bioglass as a control. After immersion, surface analyses were performed using thin-film X-ray diffraction (TF-XRD), scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDS) and Fourier-transform infrared (reflection) spectroscopy (FT-IR). All compositions showed the formation of a calcium phosphate rich surface layer in SBF; GST, GP2 and the bioglass control within 7 days of immersion and GC5 after 14 days. It was concluded that all compositions were likely to be osteoconductive in vivo, with GP2 providing the best performance in terms of the combination of rapid formation of the surface layer and superior mechanical properties. This glass-ceramic system has potential as a load bearing bioceramic for fabrication of medical devices intended for skeletal tissue repair.

UI MeSH Term Description Entries
D007101 Immersion The placing of a body or a part thereof into a liquid. Submersion,Immersions,Submersions
D008422 Materials Testing The testing of materials and devices, especially those used for PROSTHESES AND IMPLANTS; SUTURES; TISSUE ADHESIVES; etc., for hardness, strength, durability, safety, efficacy, and biocompatibility. Biocompatibility Testing,Biocompatible Materials Testing,Hemocompatibility Testing,Testing, Biocompatible Materials,Testing, Hemocompatible Materials,Hemocompatibility Testings,Hemocompatible Materials Testing,Materials Testing, Biocompatible,Materials Testing, Hemocompatible,Testing, Biocompatibility,Testing, Hemocompatibility,Testing, Materials,Testings, Biocompatibility
D008855 Microscopy, Electron, Scanning Microscopy in which the object is examined directly by an electron beam scanning the specimen point-by-point. The image is constructed by detecting the products of specimen interactions that are projected above the plane of the sample, such as backscattered electrons. Although SCANNING TRANSMISSION ELECTRON MICROSCOPY also scans the specimen point by point with the electron beam, the image is constructed by detecting the electrons, or their interaction products that are transmitted through the sample plane, so that is a form of TRANSMISSION ELECTRON MICROSCOPY. Scanning Electron Microscopy,Electron Scanning Microscopy,Electron Microscopies, Scanning,Electron Microscopy, Scanning,Electron Scanning Microscopies,Microscopies, Electron Scanning,Microscopies, Scanning Electron,Microscopy, Electron Scanning,Microscopy, Scanning Electron,Scanning Electron Microscopies,Scanning Microscopies, Electron,Scanning Microscopy, Electron
D001826 Body Fluids Liquid components of living organisms. Body Fluid,Fluid, Body,Fluids, Body
D001843 Bone Cements Adhesives used to fix prosthetic devices to bones and to cement bone to bone in difficult fractures. Synthetic resins are commonly used as cements. A mixture of monocalcium phosphate, monohydrate, alpha-tricalcium phosphate, and calcium carbonate with a sodium phosphate solution is also a useful bone paste. Bone Cement,Bone Glues,Bone Pastes,Bone Glue,Bone Paste,Cement, Bone,Cements, Bone,Glue, Bone,Glues, Bone,Paste, Bone,Pastes, Bone
D001861 Bone Regeneration Renewal or repair of lost bone tissue. It excludes BONY CALLUS formed after BONE FRACTURES but not yet replaced by hard bone. Osteoconduction,Bone Regenerations,Regeneration, Bone,Regenerations, Bone
D002516 Ceramics Products made by baking or firing nonmetallic minerals (clay and similar materials). In making dental restorations or parts of restorations the material is fused porcelain. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed & Boucher's Clinical Dental Terminology, 4th ed) Ceramic
D005544 Forecasting The prediction or projection of the nature of future problems or existing conditions based upon the extrapolation or interpretation of existing scientific data or by the application of scientific methodology. Futurology,Projections and Predictions,Future,Predictions and Projections
D001672 Biocompatible Materials Synthetic or natural materials, other than DRUGS, that are used to replace or repair any body TISSUES or bodily function. Biomaterials,Bioartificial Materials,Hemocompatible Materials,Bioartificial Material,Biocompatible Material,Biomaterial,Hemocompatible Material,Material, Bioartificial,Material, Biocompatible,Material, Hemocompatible
D013499 Surface Properties Characteristics or attributes of the outer boundaries of objects, including molecules. Properties, Surface,Property, Surface,Surface Property

Related Publications

Shashwat Bhakta, and Deepak K Pattanayak, and Hiroaki Takadama, and Tadashi Kokubo, and Cheryl A Miller, and Mehdi Mirsaneh, and Ian M Reaney, and Ian Brook, and Richard van Noort, and Paul V Hatton
In vitro biocompatibility of modified potassium fluorrichterite and potassium fluorrichterite-fluorapatite glass-ceramics.
September 2011, Journal of materials science. Materials in medicine,
Shashwat Bhakta, and Deepak K Pattanayak, and Hiroaki Takadama, and Tadashi Kokubo, and Cheryl A Miller, and Mehdi Mirsaneh, and Ian M Reaney, and Ian Brook, and Richard van Noort, and Paul V Hatton
Determination of relative in vivo osteoconductivity of modified potassium fluorrichterite glass-ceramics compared with 45S5 bioglass.
October 2012, Journal of materials science. Materials in medicine,
Shashwat Bhakta, and Deepak K Pattanayak, and Hiroaki Takadama, and Tadashi Kokubo, and Cheryl A Miller, and Mehdi Mirsaneh, and Ian M Reaney, and Ian Brook, and Richard van Noort, and Paul V Hatton
Formation of apatite layers on modified canasite glass-ceramics in simulated body fluid.
March 2002, Journal of biomedical materials research,
Shashwat Bhakta, and Deepak K Pattanayak, and Hiroaki Takadama, and Tadashi Kokubo, and Cheryl A Miller, and Mehdi Mirsaneh, and Ian M Reaney, and Ian Brook, and Richard van Noort, and Paul V Hatton
Evaluation of apatite ceramics containing alpha-tricalcium phosphate by immersion in simulated body fluid.
January 2003, Bio-medical materials and engineering,
Shashwat Bhakta, and Deepak K Pattanayak, and Hiroaki Takadama, and Tadashi Kokubo, and Cheryl A Miller, and Mehdi Mirsaneh, and Ian M Reaney, and Ian Brook, and Richard van Noort, and Paul V Hatton
Elastic constants, Vickers hardness, and fracture toughness of fluorrichterite-based glass-ceramics.
March 2004, Dental materials : official publication of the Academy of Dental Materials,
Shashwat Bhakta, and Deepak K Pattanayak, and Hiroaki Takadama, and Tadashi Kokubo, and Cheryl A Miller, and Mehdi Mirsaneh, and Ian M Reaney, and Ian Brook, and Richard van Noort, and Paul V Hatton
Crystallization processes at the surface of polylactic acid-bioactive glass composites during immersion in simulated body fluid.
November 2011, Journal of biomedical materials research. Part B, Applied biomaterials,
Shashwat Bhakta, and Deepak K Pattanayak, and Hiroaki Takadama, and Tadashi Kokubo, and Cheryl A Miller, and Mehdi Mirsaneh, and Ian M Reaney, and Ian Brook, and Richard van Noort, and Paul V Hatton
Effect of crystallization heat treatment on the microstructure and biaxial strength of fluorrichterite glass-ceramics.
February 2007, Journal of biomedical materials research. Part B, Applied biomaterials,
Shashwat Bhakta, and Deepak K Pattanayak, and Hiroaki Takadama, and Tadashi Kokubo, and Cheryl A Miller, and Mehdi Mirsaneh, and Ian M Reaney, and Ian Brook, and Richard van Noort, and Paul V Hatton
Surface Analysis of Biodegradable Mg-Alloys after Immersion in Simulated Body Fluid.
April 2020, Materials (Basel, Switzerland),
Shashwat Bhakta, and Deepak K Pattanayak, and Hiroaki Takadama, and Tadashi Kokubo, and Cheryl A Miller, and Mehdi Mirsaneh, and Ian M Reaney, and Ian Brook, and Richard van Noort, and Paul V Hatton
In vivo study of novel biodegradable and osteoconductive CaO-SiO2-B2O3 glass-ceramics.
May 2006, Journal of biomedical materials research. Part A,
Shashwat Bhakta, and Deepak K Pattanayak, and Hiroaki Takadama, and Tadashi Kokubo, and Cheryl A Miller, and Mehdi Mirsaneh, and Ian M Reaney, and Ian Brook, and Richard van Noort, and Paul V Hatton
[An experimental study on the osteoconductive properties of porous calcium phosphate glass ceramics].
November 1989, Nihon Seikeigeka Gakkai zasshi,
Copied contents to your clipboard!