Use of audio signals derived from electroencephalographic recordings as a novel 'depth of anaesthesia' monitor. 2010

John Glen
West of Scotland School of Anaesthesia, United Kingdom. johnglen@doctors.org.uk

Awareness under anaesthesia is an uncommon but serious phenomenon, which continues to occur despite the use of commercially available depth-of-anaesthesia (DOA) monitors. Many of these monitors use processed electroencephalographic (EEG) data to give an indication of anaesthetic depth. They all suffer from error due to electrical interference, individual variation and the inevitable inaccuracy inherent in the rendering of complex waveforms into a simplified digital score. It is recognised that, in the processing of complex analogue audio waveforms (i.e. sound), the human ear consistently outperforms the computer. I hypothesise that an audio signal derived from the raw EEG waveform could form the basis of a DOA monitor, enabling humans to directly determine whether a patient is awake or anaesthetised from sound alone. I propose to call the sounds derived from amplification of the EEG trace the 'audio EEG'.

UI MeSH Term Description Entries
D004569 Electroencephalography Recording of electric currents developed in the brain by means of electrodes applied to the scalp, to the surface of the brain, or placed within the substance of the brain. EEG,Electroencephalogram,Electroencephalograms
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000758 Anesthesia A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.
D001364 Awareness The act of "taking account" of an object or state of affairs. It does not imply assessment of, nor attention to the qualities or nature of the object. Situation Awareness,Situational Awareness,Awareness, Situation,Awareness, Situational,Awarenesses,Awarenesses, Situation,Awarenesses, Situational,Situation Awarenesses,Situational Awarenesses
D012815 Signal Processing, Computer-Assisted Computer-assisted processing of electric, ultrasonic, or electronic signals to interpret function and activity. Digital Signal Processing,Signal Interpretation, Computer-Assisted,Signal Processing, Digital,Computer-Assisted Signal Interpretation,Computer-Assisted Signal Interpretations,Computer-Assisted Signal Processing,Interpretation, Computer-Assisted Signal,Interpretations, Computer-Assisted Signal,Signal Interpretation, Computer Assisted,Signal Interpretations, Computer-Assisted,Signal Processing, Computer Assisted
D016343 Monitoring, Intraoperative The constant checking on the state or condition of a patient during the course of a surgical operation (e.g., checking of vital signs). Intraoperative Monitoring

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