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1. In order to introduce antitetanus immunoglobulin fragments into eukaryotic cells, either antitetanus F(ab')2 or Fab' fragments have been linked to carrier molecules. Aciclovir, horseradish peroxidase, wheat germ agglutinin, and transferrin were tried as carriers. 2. F(ab')2-aciclovir and Fab'-horseradish peroxidase were not internalized by NG108-15 neurohybridoma cells. 3. [Fab']2-wheat germ agglutinin and F(ab')2-transferrin conjugates were internalized into various cells. 4. F(ab')2-transferrin conjugates were made with three different linkers: N-succinimidyl 3-(2-pyridyldithio) propionate, bis-maleimido hexane, and bis-maleimidoethoxy propane. All three conjugates were internalized but had a different fate inside the cells.
H H Wellhöner, and
H Bigalke, and
T Borcholte, and
G Erdmann, and
T Eschenhagen, and
K H Jung, and
P Marxen, and
U Peukert, and
D M Neville, and
K Srinivasachar
October 1994,
Biotechnology and applied biochemistry,
H H Wellhöner, and
H Bigalke, and
T Borcholte, and
G Erdmann, and
T Eschenhagen, and
K H Jung, and
P Marxen, and
U Peukert, and
D M Neville, and
K Srinivasachar
August 2008,
Bioconjugate chemistry,
H H Wellhöner, and
H Bigalke, and
T Borcholte, and
G Erdmann, and
T Eschenhagen, and
K H Jung, and
P Marxen, and
U Peukert, and
D M Neville, and
K Srinivasachar
November 1983,
Clinical chemistry,
H H Wellhöner, and
H Bigalke, and
T Borcholte, and
G Erdmann, and
T Eschenhagen, and
K H Jung, and
P Marxen, and
U Peukert, and
D M Neville, and
K Srinivasachar
July 1984,
Molecular immunology,
H H Wellhöner, and
H Bigalke, and
T Borcholte, and
G Erdmann, and
T Eschenhagen, and
K H Jung, and
P Marxen, and
U Peukert, and
D M Neville, and
K Srinivasachar
October 1972,
Journal of immunology (Baltimore, Md. : 1950),
H H Wellhöner, and
H Bigalke, and
T Borcholte, and
G Erdmann, and
T Eschenhagen, and
K H Jung, and
P Marxen, and
U Peukert, and
D M Neville, and
K Srinivasachar
June 1990,
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
H H Wellhöner, and
H Bigalke, and
T Borcholte, and
G Erdmann, and
T Eschenhagen, and
K H Jung, and
P Marxen, and
U Peukert, and
D M Neville, and
K Srinivasachar
January 2007,
Zhurnal mikrobiologii, epidemiologii i immunobiologii,
H H Wellhöner, and
H Bigalke, and
T Borcholte, and
G Erdmann, and
T Eschenhagen, and
K H Jung, and
P Marxen, and
U Peukert, and
D M Neville, and
K Srinivasachar
January 1996,
Seikagaku. The Journal of Japanese Biochemical Society,
H H Wellhöner, and
H Bigalke, and
T Borcholte, and
G Erdmann, and
T Eschenhagen, and
K H Jung, and
P Marxen, and
U Peukert, and
D M Neville, and
K Srinivasachar
May 1986,
Biulleten' eksperimental'noi biologii i meditsiny,
H H Wellhöner, and
H Bigalke, and
T Borcholte, and
G Erdmann, and
T Eschenhagen, and
K H Jung, and
P Marxen, and
U Peukert, and
D M Neville, and
K Srinivasachar
January 1984,
Immunological communications,
