Biomaterial Database

Optic nerve enlargement in acute optic neuritis. 1990

R E Steg, and D M Lefkowitz, and Z Wszolek, and A A Jordan

Department of Neurology, Creighton University School of Medicine, Omaha, NE 68131.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D009103	Multiple Sclerosis	An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)	MS (Multiple Sclerosis),Multiple Sclerosis, Acute Fulminating,Sclerosis, Disseminated,Disseminated Sclerosis,Sclerosis, Multiple
D009900	Optic Nerve	The 2nd cranial nerve which conveys visual information from the RETINA to the brain. The nerve carries the axons of the RETINAL GANGLION CELLS which sort at the OPTIC CHIASM and continue via the OPTIC TRACTS to the brain. The largest projection is to the lateral geniculate nuclei; other targets include the SUPERIOR COLLICULI and the SUPRACHIASMATIC NUCLEI. Though known as the second cranial nerve, it is considered part of the CENTRAL NERVOUS SYSTEM.	Cranial Nerve II,Second Cranial Nerve,Nervus Opticus,Cranial Nerve, Second,Cranial Nerves, Second,Nerve, Optic,Nerve, Second Cranial,Nerves, Optic,Nerves, Second Cranial,Optic Nerves,Second Cranial Nerves
D009902	Optic Neuritis	Inflammation of the optic nerve. Commonly associated conditions include autoimmune disorders such as MULTIPLE SCLEROSIS, infections, and granulomatous diseases. Clinical features include retro-orbital pain that is aggravated by eye movement, loss of color vision, and contrast sensitivity that may progress to severe visual loss, an afferent pupillary defect (Marcus-Gunn pupil), and in some instances optic disc hyperemia and swelling. Inflammation may occur in the portion of the nerve within the globe (neuropapillitis or anterior optic neuritis) or the portion behind the globe (retrobulbar neuritis or posterior optic neuritis).	Neuropapillitis,Retrobulbar Neuritis,Anterior Optic Neuritis,Posterior Optic Neuritis,Anterior Optic Neuritides,Neuritides, Anterior Optic,Neuritides, Optic,Neuritides, Posterior Optic,Neuritides, Retrobulbar,Neuritis, Anterior Optic,Neuritis, Optic,Neuritis, Posterior Optic,Neuritis, Retrobulbar,Neuropapillitides,Optic Neuritides,Optic Neuritides, Anterior,Optic Neuritides, Posterior,Optic Neuritis, Anterior,Optic Neuritis, Posterior,Posterior Optic Neuritides,Retrobulbar Neuritides
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000208	Acute Disease	Disease having a short and relatively severe course.	Acute Diseases,Disease, Acute,Diseases, Acute
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults

Related Publications

R E Steg, and D M Lefkowitz, and Z Wszolek, and A A Jordan

MRI of optic nerve enlargement in optic neuritis.

April 1997, Neurology,

R E Steg, and D M Lefkowitz, and Z Wszolek, and A A Jordan

Enlargement of optic nerve resembling orbital mass in case of optic neuritis.

June 2007, Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie,

R E Steg, and D M Lefkowitz, and Z Wszolek, and A A Jordan

The optic nerve sheath on MRI in acute optic neuritis.

January 2005, Neuroradiology,

R E Steg, and D M Lefkowitz, and Z Wszolek, and A A Jordan

[Optic nerve neuritis].

August 2013, Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft,

R E Steg, and D M Lefkowitz, and Z Wszolek, and A A Jordan

Calpain inhibitor attenuated optic nerve damage in acute optic neuritis in rats.

January 2013, Journal of neurochemistry,

R E Steg, and D M Lefkowitz, and Z Wszolek, and A A Jordan

[Acute ischemic optic neuritis. Arterio-axial syndrome of the optic nerve].

December 1967, Revue d'oto-neuro-ophtalmologie,