Improvement in Fourier analysis of gated blood-pool studies using single photon emission computed tomography: methodology and clinical feasibility. 1990

H Maeda, and K Takeda, and T Ito, and T Nakagawa, and T Konishi, and T Kondo, and H Toyama, and G Takeshita, and A Takeuchi
Department of Radiological Technology, Fujita Health University School of Hygiene, Aichi, Japan.

We have developed a new method for obtaining reconstructed left ventricular (LV) planar images acquired from multidirectional views using gated blood-pool single photon emission computed tomography (SPECT), and have applied Fourier analysis to these planar images. In this paper, we describe the methodology of our new technique and discuss its feasibility for the detection of LV wall motion abnormalities (WMA) in patients with coronary artery disease (CAD). Sagittal long-axis, horizontal long-axis and short-axis sections of the LV were generated from the reconstructed transaxial tomograms. Sections covering only the LV at the same phase of the cardiac cycle were added to reconstruct planar images. Fourier analysis was then performed to construct phase and amplitude images. In 42 patients with significant WMA, a comparative study concerning the detection of WMA was performed between conventional and SPECT methods. The SPECT method had greater sensitivity in all segments of the LV, with no significant loss in specificity. In particular, the sensitivity of the SPECT method was significantly greater than that of the conventional method for inferior and posterior WMA (91% vs 57%; and 76% vs 35%, respectively). The method described here shows greater clinical effectiveness for the detection of LV WMA in patients with CAD.

UI MeSH Term Description Entries
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009200 Myocardial Contraction Contractile activity of the MYOCARDIUM. Heart Contractility,Inotropism, Cardiac,Cardiac Inotropism,Cardiac Inotropisms,Contractilities, Heart,Contractility, Heart,Contraction, Myocardial,Contractions, Myocardial,Heart Contractilities,Inotropisms, Cardiac,Myocardial Contractions
D003327 Coronary Disease An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels. Coronary Heart Disease,Coronary Diseases,Coronary Heart Diseases,Disease, Coronary,Disease, Coronary Heart,Diseases, Coronary,Diseases, Coronary Heart,Heart Disease, Coronary,Heart Diseases, Coronary
D005583 Fourier Analysis Analysis based on the mathematical function first formulated by Jean-Baptiste-Joseph Fourier in 1807. The function, known as the Fourier transform, describes the sinusoidal pattern of any fluctuating pattern in the physical world in terms of its amplitude and its phase. It has broad applications in biomedicine, e.g., analysis of the x-ray crystallography data pivotal in identifying the double helical nature of DNA and in analysis of other molecules, including viruses, and the modified back-projection algorithm universally used in computerized tomography imaging, etc. (From Segen, The Dictionary of Modern Medicine, 1992) Fourier Series,Fourier Transform,Analysis, Cyclic,Analysis, Fourier,Cyclic Analysis,Analyses, Cyclic,Cyclic Analyses,Series, Fourier,Transform, Fourier
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly
D015637 Gated Blood-Pool Imaging Radionuclide ventriculography where scintigraphic data is acquired during repeated cardiac cycles at specific times in the cycle, using an electrocardiographic synchronizer or gating device. Analysis of right ventricular function is difficult with this technique; that is best evaluated by first-pass ventriculography (VENTRICULOGRAPHY, FIRST-PASS). Angiography, Gated Radionuclide,Equilibrium Radionuclide Angiography,Equilibrium Radionuclide Ventriculography,Gated Blood-Pool Scintigraphy,Gated Equilibrium Blood-Pool Scintigraphy,Radionuclide Angiography, Gated,Radionuclide Ventriculography, Gated,Scintigraphy, Equilibrium,Ventriculography, Equilibrium Radionuclide,Ventriculography, Gated Radionuclide,Blood-Pool Scintigraphy,Equilibrium Radionuclide Angiocardiography,Gated Equilibrium Blood Pool Scintigraphy,Angiocardiographies, Equilibrium Radionuclide,Angiocardiography, Equilibrium Radionuclide,Angiographies, Equilibrium Radionuclide,Angiographies, Gated Radionuclide,Angiography, Equilibrium Radionuclide,Blood Pool Scintigraphy,Blood-Pool Imaging, Gated,Blood-Pool Imagings, Gated,Blood-Pool Scintigraphies,Blood-Pool Scintigraphies, Gated,Blood-Pool Scintigraphy, Gated,Equilibrium Radionuclide Angiocardiographies,Equilibrium Radionuclide Angiographies,Equilibrium Radionuclide Ventriculographies,Equilibrium Scintigraphies,Equilibrium Scintigraphy,Gated Blood Pool Imaging,Gated Blood Pool Scintigraphy,Gated Blood-Pool Imagings,Gated Blood-Pool Scintigraphies,Gated Radionuclide Angiographies,Gated Radionuclide Angiography,Gated Radionuclide Ventriculographies,Gated Radionuclide Ventriculography,Imaging, Gated Blood-Pool,Imagings, Gated Blood-Pool,Radionuclide Angiocardiographies, Equilibrium,Radionuclide Angiocardiography, Equilibrium,Radionuclide Angiographies, Equilibrium,Radionuclide Angiographies, Gated,Radionuclide Angiography, Equilibrium,Radionuclide Ventriculographies, Equilibrium,Radionuclide Ventriculographies, Gated,Radionuclide Ventriculography, Equilibrium,Scintigraphies, Blood-Pool,Scintigraphies, Equilibrium,Scintigraphies, Gated Blood-Pool,Scintigraphy, Blood-Pool,Scintigraphy, Gated Blood-Pool,Ventriculographies, Equilibrium Radionuclide,Ventriculographies, Gated Radionuclide
D015899 Tomography, Emission-Computed, Single-Photon A method of computed tomography that uses radionuclides which emit a single photon of a given energy. The camera is rotated 180 or 360 degrees around the patient to capture images at multiple positions along the arc. The computer is then used to reconstruct the transaxial, sagittal, and coronal images from the 3-dimensional distribution of radionuclides in the organ. The advantages of SPECT are that it can be used to observe biochemical and physiological processes as well as size and volume of the organ. The disadvantage is that, unlike positron-emission tomography where the positron-electron annihilation results in the emission of 2 photons at 180 degrees from each other, SPECT requires physical collimation to line up the photons, which results in the loss of many available photons and hence degrades the image. CAT Scan, Single-Photon Emission,CT Scan, Single-Photon Emission,Radionuclide Tomography, Single-Photon Emission-Computed,SPECT,Single-Photon Emission-Computed Tomography,Tomography, Single-Photon, Emission-Computed,Single-Photon Emission CT Scan,Single-Photon Emission Computer-Assisted Tomography,Single-Photon Emission Computerized Tomography,CAT Scan, Single Photon Emission,CT Scan, Single Photon Emission,Emission-Computed Tomography, Single-Photon,Radionuclide Tomography, Single Photon Emission Computed,Single Photon Emission CT Scan,Single Photon Emission Computed Tomography,Single Photon Emission Computer Assisted Tomography,Single Photon Emission Computerized Tomography,Tomography, Single-Photon Emission-Computed

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