Biomaterial Database

[Determination of lymphocyte receptors to Klebsiella in ankylosing spondylitis]. 1990

A G Belen'kii, and V G Davtian

The authors give the results of determining receptors to Klebsiella antigens on the surface of the peripheral blood lymphocytes in ankylosing spondyloarthritis (AS). They examined 21 patients with AS, 20 patients with rheumatoid arthritis (RA) and 20 healthy individuals. Determination of the receptors was done in the reaction of indirect rosette formation. An ultrasonic disintegrate of Klebsiella culture isolated from a patient with AS was used as an antigen. Favourable results were obtained in 10 patients with AS and in none of the cases in the group of patients with RA and in healthy individuals. A higher specificity of the reaction of antigen binding lymphocytes was shown.

UI	MeSH Term	Description	Entries
D007709	Klebsiella	A genus of gram-negative, facultatively anaerobic, rod-shaped bacteria whose organisms arrange singly, in pairs, or short chains. This genus is commonly found in the intestinal tract and is an opportunistic pathogen that can give rise to bacteremia, pneumonia, urinary tract and several other types of human infection.
D008214	Lymphocytes	White blood cells formed in the body's lymphoid tissue. The nucleus is round or ovoid with coarse, irregularly clumped chromatin while the cytoplasm is typically pale blue with azurophilic (if any) granules. Most lymphocytes can be classified as either T or B (with subpopulations of each), or NATURAL KILLER CELLS.	Lymphoid Cells,Cell, Lymphoid,Cells, Lymphoid,Lymphocyte,Lymphoid Cell
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D011946	Receptors, Antigen	Molecules on the surface of B- and T-lymphocytes that recognize and combine with specific antigens.	Antigen Receptors,Antigen Receptor,Receptor, Antigen
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293	Adolescent	A person 13 to 18 years of age.	Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D000942	Antigens, Bacterial	Substances elaborated by bacteria that have antigenic activity.	Bacterial Antigen,Bacterial Antigens,Antigen, Bacterial