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Laser hyperthermia using Nd-YAG laser was studied experimentally and clinically to treat deep-seated brain tumors. Histological changes, temperature profile, and modification of the blood-brain barrier were studied using cat and rat brains. In a clinical study 5 patients with brain tumors were treated with laser hyperthermia using this computed tomography-stereotactic technique. All tumors of these patients disappeared on computed tomography, and 3 of the 5 patients are still alive without recurrence. It was possible to make optimal lesion and to have accurate peripheral temperature control by using the combination of the Komai stereotactic method and the SLT Nd-YAG laser system. Interstitial laser hyperthermia using this method is easy and safe to use, and it is beneficial to treat deep-seated brain tumors.
K Sugiyama, and
T Sakai, and
I Fujishima, and
H Ryu, and
K Uemura, and
T Yokoyama
January 1991,
Scandinavian journal of urology and nephrology. Supplementum,
K Sugiyama, and
T Sakai, and
I Fujishima, and
H Ryu, and
K Uemura, and
T Yokoyama
March 1987,
Gan to kagaku ryoho. Cancer & chemotherapy,
K Sugiyama, and
T Sakai, and
I Fujishima, and
H Ryu, and
K Uemura, and
T Yokoyama
November 1988,
[Hokkaido igaku zasshi] The Hokkaido journal of medical science,
K Sugiyama, and
T Sakai, and
I Fujishima, and
H Ryu, and
K Uemura, and
T Yokoyama
October 2000,
Journal of reconstructive microsurgery,
K Sugiyama, and
T Sakai, and
I Fujishima, and
H Ryu, and
K Uemura, and
T Yokoyama
September 1983,
Ophthalmology,
K Sugiyama, and
T Sakai, and
I Fujishima, and
H Ryu, and
K Uemura, and
T Yokoyama
January 1988,
Lasers in surgery and medicine,
K Sugiyama, and
T Sakai, and
I Fujishima, and
H Ryu, and
K Uemura, and
T Yokoyama
January 1998,
Lasers in surgery and medicine,
K Sugiyama, and
T Sakai, and
I Fujishima, and
H Ryu, and
K Uemura, and
T Yokoyama
April 1986,
Gastrointestinal endoscopy,
K Sugiyama, and
T Sakai, and
I Fujishima, and
H Ryu, and
K Uemura, and
T Yokoyama
January 1999,
International ophthalmology clinics,
K Sugiyama, and
T Sakai, and
I Fujishima, and
H Ryu, and
K Uemura, and
T Yokoyama
February 1984,
MMW, Munchener medizinische Wochenschrift,
