Biomaterial Database

Distinct photoacidity of honokiol from magnolol. 2011

Hongmei Li, and Xianfeng Wang, and Yuzhu Hu

School of Basic Science, China Pharmaceutical University, Nanjing, China. Lihongm2001@hotmail.com

Honokiol, 5,5'-diallyl-2,4'-dihydroxy- biphenyl, by comparison with its isomer magnolol, 5,5'-diallyl- 2,2'-dihydroxy- biphenyl, has been characterized by steady-state and time-resolved spectroscopy as well as (1)H NMR. Honokiol shows more complex pH dependence of absorption and fluorescence characteristics compared with magnolol. Honokiol possesses much weaker acidity than magnolol both in the ground and excited states. Its weak photoacidity is similar to that of 4-hydroxy- biphenyl or 4, 4'-dihydroxy- biphenyl rather than 2-hydroxy- biphenyl or 2, 2'-hydroxy- biphenyl. The electron effect and geometry configuration of substitution has been discussed.

UI	MeSH Term	Description	Entries
D009682	Magnetic Resonance Spectroscopy	Spectroscopic method of measuring the magnetic moment of elementary particles such as atomic nuclei, protons or electrons. It is employed in clinical applications such as NMR Tomography (MAGNETIC RESONANCE IMAGING).	In Vivo NMR Spectroscopy,MR Spectroscopy,Magnetic Resonance,NMR Spectroscopy,NMR Spectroscopy, In Vivo,Nuclear Magnetic Resonance,Spectroscopy, Magnetic Resonance,Spectroscopy, NMR,Spectroscopy, Nuclear Magnetic Resonance,Magnetic Resonance Spectroscopies,Magnetic Resonance, Nuclear,NMR Spectroscopies,Resonance Spectroscopy, Magnetic,Resonance, Magnetic,Resonance, Nuclear Magnetic,Spectroscopies, NMR,Spectroscopy, MR
D010777	Photochemistry	A branch of physical chemistry which studies chemical reactions, isomerization and physical behavior that may occur under the influence of visible and/or ultraviolet light.	Photochemistries
D006863	Hydrogen-Ion Concentration	The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH	pH,Concentration, Hydrogen-Ion,Concentrations, Hydrogen-Ion,Hydrogen Ion Concentration,Hydrogen-Ion Concentrations
D000143	Acids	Chemical compounds which yield hydrogen ions or protons when dissolved in water, whose hydrogen can be replaced by metals or basic radicals, or which react with bases to form salts and water (neutralization). An extension of the term includes substances dissolved in media other than water. (Grant & Hackh's Chemical Dictionary, 5th ed)	Acid
D001713	Biphenyl Compounds	Whitish aromatic crystalline organic compounds made up of two conjoined BENZENE rings.	Compounds, Biphenyl
D013050	Spectrometry, Fluorescence	Measurement of the intensity and quality of fluorescence.	Fluorescence Spectrophotometry,Fluorescence Spectroscopy,Spectrofluorometry,Fluorescence Spectrometry,Spectrophotometry, Fluorescence,Spectroscopy, Fluorescence
D017705	Lignans	A class of dibenzylbutane derivatives which occurs in higher plants and in fluids (bile, serum, urine, etc.) in man and other animals. These compounds, which have a potential anti-cancer role, can be synthesized in vitro by human fecal flora. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)	Lignan,Neolignan,Neolignans