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Oxytocic peptides extracted from the brain and plasma of the brushtail possum, Trichosurus vulpecula, were separated by reverse-phase high pressure lipid chromatography (HPLC) and quantified by specific radioimmunoassays for oxytocin (OT) and mesotocin (MT). The pituitary, hypothalamus and cerebral cortex were found to contain MT only in quantities of 3.9 +/- 0.2 (SE) ug, 17.6 +/- 0.6 ng and 21.0 +/- 2.6 ng respectively. The plasma concentration of MT varied according to the degree of stress of the possum. In anaesthetized animals values of 39.7 +/- 9.7 pg/ml (11 males) and 31.5 +/- 12.9 pg/ml (6 females) were obtained; in four conscious catheterized animals, 9.4 +/- 6.3 pg/ml. Samples taken from three anaesthetized animals during exsanguination contained 271 +/- 102 (SD) pg MT/ml. It was concluded that hypothalamic and extra-hypothalamic MT is present in the marsupial brain and that as in placental mammals, stress stimulates the secretion of mesotocin.
R A Bathgate, and
C Sernia, and
R T Gemmell
January 1990,
General and comparative endocrinology,
R A Bathgate, and
C Sernia, and
R T Gemmell
January 1990,
Comparative biochemistry and physiology. A, Comparative physiology,
R A Bathgate, and
C Sernia, and
R T Gemmell
July 1997,
Archives of environmental contamination and toxicology,
R A Bathgate, and
C Sernia, and
R T Gemmell
September 1997,
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology,
R A Bathgate, and
C Sernia, and
R T Gemmell
October 1993,
Comparative biochemistry and physiology. Comparative physiology,
R A Bathgate, and
C Sernia, and
R T Gemmell
January 1998,
DNA sequence : the journal of DNA sequencing and mapping,
R A Bathgate, and
C Sernia, and
R T Gemmell
July 2001,
Immunogenetics,
R A Bathgate, and
C Sernia, and
R T Gemmell
December 1998,
Molecular ecology,
R A Bathgate, and
C Sernia, and
R T Gemmell
April 1994,
New Zealand veterinary journal,
R A Bathgate, and
C Sernia, and
R T Gemmell
March 2001,
Journal of virology,
