[The effect of chronic internal irradiation from incorporated radionuclides on liver function]. 1990

I K Dedenko, and M P Zakharash, and O N Ganich, and L T Siksaĭ, and R I Shnitser, and G I Sofienko, and N N Bytsaĭ, and V S Zemskov, and V I Trunov, and V N Bukanov

On chronic supply to the body of a mixture of nuclear division products lanthanum-140, barium-140, tellurium-132, neodymium-147, neptunium-239, zirconium-95, niobium-95, iodine-131, cerium-141, -144, cesium-134, -137, and ruthenium-103 are detectable in liver tissue within the first months. In the 2 to 4 years following the disaster, liver tissue primarily accumulates cerium-144, radium-226, thorium-228, -232, ruthenium-106, antimony-125, and europium-154. Within the first periods the liver radionuclide content was 19 to 31% higher than that in the blood, and in the following years it was 24 to 38% higher. The radionuclides indicated were actively excreted with the bile into the gastrointestinal lumen. Within the first months after the chronic internal radiation the functional liver disorders were detectable in 30 to 40% of the patients. Later on diverse acute and chronic diseases of the liver, gallbladder and pancreas were detectable in 20 to 30% of the patients. The radionuclide content in the body was found to be in parallel with functional liver disorders. Acceleration of radionuclide excretion from the body results in liver function improvement.

UI MeSH Term Description Entries
D008099 Liver A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances. Livers
D008111 Liver Function Tests Blood tests that are used to evaluate how well a patient's liver is working and also to help diagnose liver conditions. Function Test, Liver,Function Tests, Liver,Liver Function Test,Test, Liver Function,Tests, Liver Function
D011832 Radiation Injuries Harmful effects of non-experimental exposure to ionizing or non-ionizing radiation in VERTEBRATES. Radiation Sickness,Radiation Syndrome,Injuries, Radiation,Injury, Radiation,Radiation Injury,Radiation Sicknesses,Radiation Syndromes,Sickness, Radiation,Sicknesses, Radiation,Syndrome, Radiation,Syndromes, Radiation
D011868 Radioisotopes Isotopes that exhibit radioactivity and undergo radioactive decay. (From Grant & Hackh's Chemical Dictionary, 5th ed & McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Daughter Isotope,Daughter Nuclide,Radioactive Isotope,Radioactive Isotopes,Radiogenic Isotope,Radioisotope,Radionuclide,Radionuclides,Daughter Nuclides,Daugter Isotopes,Radiogenic Isotopes,Isotope, Daughter,Isotope, Radioactive,Isotope, Radiogenic,Isotopes, Daugter,Isotopes, Radioactive,Isotopes, Radiogenic,Nuclide, Daughter,Nuclides, Daughter
D002908 Chronic Disease Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2). Chronic Condition,Chronic Illness,Chronically Ill,Chronic Conditions,Chronic Diseases,Chronic Illnesses,Condition, Chronic,Disease, Chronic,Illness, Chronic
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001646 Bile An emulsifying agent produced in the LIVER and secreted into the DUODENUM. Its composition includes BILE ACIDS AND SALTS; CHOLESTEROL; and ELECTROLYTES. It aids DIGESTION of fats in the duodenum. Biliary Sludge,Sludge, Biliary
D013997 Time Factors Elements of limited time intervals, contributing to particular results or situations. Time Series,Factor, Time,Time Factor
D016273 Occupational Exposure The exposure to potentially harmful chemical, physical, or biological agents that occurs as a result of one's occupation. Exposure, Occupational,Exposures, Occupational,Occupational Exposures

Related Publications

I K Dedenko, and M P Zakharash, and O N Ganich, and L T Siksaĭ, and R I Shnitser, and G I Sofienko, and N N Bytsaĭ, and V S Zemskov, and V I Trunov, and V N Bukanov
January 2018, Radiation research,
I K Dedenko, and M P Zakharash, and O N Ganich, and L T Siksaĭ, and R I Shnitser, and G I Sofienko, and N N Bytsaĭ, and V S Zemskov, and V I Trunov, and V N Bukanov
January 1971, Arkhiv anatomii, gistologii i embriologii,
I K Dedenko, and M P Zakharash, and O N Ganich, and L T Siksaĭ, and R I Shnitser, and G I Sofienko, and N N Bytsaĭ, and V S Zemskov, and V I Trunov, and V N Bukanov
August 1973, Strahlentherapie,
I K Dedenko, and M P Zakharash, and O N Ganich, and L T Siksaĭ, and R I Shnitser, and G I Sofienko, and N N Bytsaĭ, and V S Zemskov, and V I Trunov, and V N Bukanov
January 1973, Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin,
I K Dedenko, and M P Zakharash, and O N Ganich, and L T Siksaĭ, and R I Shnitser, and G I Sofienko, and N N Bytsaĭ, and V S Zemskov, and V I Trunov, and V N Bukanov
November 1988, Gigiena i sanitariia,
I K Dedenko, and M P Zakharash, and O N Ganich, and L T Siksaĭ, and R I Shnitser, and G I Sofienko, and N N Bytsaĭ, and V S Zemskov, and V I Trunov, and V N Bukanov
January 1973, Voprosy onkologii,
I K Dedenko, and M P Zakharash, and O N Ganich, and L T Siksaĭ, and R I Shnitser, and G I Sofienko, and N N Bytsaĭ, and V S Zemskov, and V I Trunov, and V N Bukanov
January 1991, Meditsinskaia radiologiia,
I K Dedenko, and M P Zakharash, and O N Ganich, and L T Siksaĭ, and R I Shnitser, and G I Sofienko, and N N Bytsaĭ, and V S Zemskov, and V I Trunov, and V N Bukanov
February 1988, Health physics,
I K Dedenko, and M P Zakharash, and O N Ganich, and L T Siksaĭ, and R I Shnitser, and G I Sofienko, and N N Bytsaĭ, and V S Zemskov, and V I Trunov, and V N Bukanov
January 2002, Radiatsionnaia biologiia, radioecologiia,
I K Dedenko, and M P Zakharash, and O N Ganich, and L T Siksaĭ, and R I Shnitser, and G I Sofienko, and N N Bytsaĭ, and V S Zemskov, and V I Trunov, and V N Bukanov
January 1970, Radiobiologiia,
Copied contents to your clipboard!