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The subcellular localization in chicken Rous sarcoma of nucleotide sequence, complementary to Rous sarcoma virus RNA was examined by RNA/RNA molecular hybridization. The preparations of radioiodinated virion RNA were annealed with RNAs from different fractions (nuclei, mitochondria, free and membrane-bound polyribosomes) isolated from chicken Rous sarcoma. Formation of RNA-ase resistant hybrids between the viral 125I-RNA and RNA from the mitochondria and membrane-bound polyribosomes was revealed. The latter were characterized by a higher relative redundancy of nucleotide sequences complementary to virion RNA than that in the former, by factor 446. The role of complementary ribonucleotide sequences is discussed.
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O K Kuznetsov
May 1977,
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Ia D Shaposhnikov, and
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Ia D Shaposhnikov, and
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Ia D Shaposhnikov, and
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Ia D Shaposhnikov, and
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Ia D Shaposhnikov, and
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Ia D Shaposhnikov, and
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June 1967,
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Ia D Shaposhnikov, and
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Ia D Shaposhnikov, and
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Ia D Shaposhnikov, and
E A Ratovitskiĭ, and
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