Comparison of the effects of argon and neodymium:YAG laser iridotomy on prostaglandin E2 and blood-aqueous barrier disruption. 1990

N Naveh, and M Rosner, and L Zborowsky-Gutman, and N Rosen, and C Weissman
Maurice and Gabriela Goldschleger Eye Research Institute, Tel Aviv University, Sackler Faculty of Medicine, Tel Hashomer, Israel.

We compared in rabbits the effects of laser iridotomy by either argon or neodymium (Nd):YAG laser on prostaglandin E2 (PGE2) production by the iris/ciliary body, its accumulation in the aqueous humor and the aqueous protein levels. PGE2 production by the iris/ciliary body, following exposure to argon or Nd:YAG laser, was similarly enhanced, with peak levels of 22.8 +/- 4.7 and 24.1 +/- 8.2 ng/mg, respectively. An increase in aqueous PGE2 levels was more pronounced in the argon as compared with the Nd:YAG group, with peak levels of 56.7 +/- 17.3 and 20.0 +/- 7.7 ng/ml, respectively. PGE2 production correlated well with aqueous PGE2 levels in the argon group, but not in the Nd:YAG group. Protein accumulated in the aqueous humor following irradiation by both types of laser light, with higher levels occurring in the argon group. These results are indicative of possible differences in the extent of the inflammatory reaction induced by the application of argon and Nd:YAG laser light to the iris.

UI MeSH Term Description Entries
D007498 Iris The most anterior portion of the uveal layer, separating the anterior chamber from the posterior. It consists of two layers - the stroma and the pigmented epithelium. Color of the iris depends on the amount of melanin in the stroma on reflection from the pigmented epithelium.
D008297 Male Males
D009354 Neodymium An element of the rare earth family of metals. It has the atomic symbol Nd, atomic number 60, and atomic weight 144.24, and is used in industrial applications.
D011817 Rabbits A burrowing plant-eating mammal with hind limbs that are longer than its fore limbs. It belongs to the family Leporidae of the order Lagomorpha, and in contrast to hares, possesses 22 instead of 24 pairs of chromosomes. Belgian Hare,New Zealand Rabbit,New Zealand Rabbits,New Zealand White Rabbit,Rabbit,Rabbit, Domestic,Chinchilla Rabbits,NZW Rabbits,New Zealand White Rabbits,Oryctolagus cuniculus,Chinchilla Rabbit,Domestic Rabbit,Domestic Rabbits,Hare, Belgian,NZW Rabbit,Rabbit, Chinchilla,Rabbit, NZW,Rabbit, New Zealand,Rabbits, Chinchilla,Rabbits, Domestic,Rabbits, NZW,Rabbits, New Zealand,Zealand Rabbit, New,Zealand Rabbits, New,cuniculus, Oryctolagus
D002924 Ciliary Body A ring of tissue extending from the scleral spur to the ora serrata of the RETINA. It consists of the uveal portion and the epithelial portion. The ciliary muscle is in the uveal portion and the ciliary processes are in the epithelial portion. Corpus Ciliare,Corpus Ciliaris,Bodies, Ciliary,Body, Ciliary,Ciliare, Corpus,Ciliares, Corpus,Ciliari, Corpus,Ciliaris, Corpus,Ciliary Bodies,Corpus Ciliares,Corpus Ciliari
D005136 Eye Proteins PROTEINS derived from TISSUES of the EYE. Proteins, Eye
D005260 Female Females
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000867 Anterior Chamber The space in the eye, filled with aqueous humor, bounded anteriorly by the cornea and a small portion of the sclera and posteriorly by a small portion of the ciliary body, the iris, and that part of the crystalline lens which presents through the pupil. (Cline et al., Dictionary of Visual Science, 4th ed, p109) Anterior Chambers,Chamber, Anterior,Chambers, Anterior
D001082 Aqueous Humor The clear, watery fluid which fills the anterior and posterior chambers of the eye. It has a refractive index lower than the crystalline lens, which it surrounds, and is involved in the metabolism of the cornea and the crystalline lens. (Cline et al., Dictionary of Visual Science, 4th ed, p319) Aqueous Flare,Intraocular Fluid,Aqueous Flares,Aqueous Humors,Flare, Aqueous,Fluid, Intraocular,Fluids, Intraocular,Humor, Aqueous,Humors, Aqueous,Intraocular Fluids

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