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Malaria parasites switch to sexual development after a period of vegetative growth in the host's erythrocytes. This switch, vital for parasite transmission to mosquitoes, is little understood at the genetic level. Likely candidates for developmental control are the alpha- and beta-tubulin subunits required for microtubule assembly. We report here that the transcription of the alpha- and beta-tubulin genes in Plasmodium falciparum show a radically different pattern of transcription in the sexual and sexual phases of parasite growth. Our studies lead to the conclusion that three transcripts of the beta-tubulin gene differ by sequences in their 5'- or 3'-untranslated regions.
C J Delves, and
P Alano, and
R G Ridley, and
M Goman, and
S P Holloway, and
J E Hyde, and
J G Scaife
June 2020,
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C J Delves, and
P Alano, and
R G Ridley, and
M Goman, and
S P Holloway, and
J E Hyde, and
J G Scaife
September 1999,
International journal for parasitology,
C J Delves, and
P Alano, and
R G Ridley, and
M Goman, and
S P Holloway, and
J E Hyde, and
J G Scaife
July 1999,
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C J Delves, and
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J G Scaife
June 2013,
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C J Delves, and
P Alano, and
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M Goman, and
S P Holloway, and
J E Hyde, and
J G Scaife
January 2010,
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C J Delves, and
P Alano, and
R G Ridley, and
M Goman, and
S P Holloway, and
J E Hyde, and
J G Scaife
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C J Delves, and
P Alano, and
R G Ridley, and
M Goman, and
S P Holloway, and
J E Hyde, and
J G Scaife
March 1988,
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C J Delves, and
P Alano, and
R G Ridley, and
M Goman, and
S P Holloway, and
J E Hyde, and
J G Scaife
March 2002,
Parasitology research,
C J Delves, and
P Alano, and
R G Ridley, and
M Goman, and
S P Holloway, and
J E Hyde, and
J G Scaife
January 2021,
Frontiers in cellular and infection microbiology,
C J Delves, and
P Alano, and
R G Ridley, and
M Goman, and
S P Holloway, and
J E Hyde, and
J G Scaife
December 1999,
The Southeast Asian journal of tropical medicine and public health,
