Experience with propafenone for the treatment of cardiac arrhythmias in children. 1990

A Celiker, and S Ozer, and S Ozme, and S Ozkutlu, and O Kahramanyol
Hacettepe University Institute of Child Health, Ankara.

The aim of this prospective study was to evaluate the efficacy of propafenone in suppressing various arrhythmias in a group of children who were patients in the Pediatric Cardiology Unit of Hacettepe University Children's Hospital. Seven of the 13 children (53.8%) with ventricular ectopics, all three children with paroxysmal re-entry atrioventricular tachycardia, and two of the three children with paroxysmal atrial tachycardia were treated successfully with propafenone. The drug did not cause any side effects or arrhythmogenesis. The median dosage of propafenone at discharge was 300 mg/m2/day (range 250-400 mg/m2/day) every eight hours. Our findings confirm the efficacy and safety of propafenone for the treatment of childhood arrhythmias.

UI MeSH Term Description Entries
D008297 Male Males
D011405 Propafenone An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity. Apo-Propafenone,Arythmol,Baxarytmon,Cuxafenon,Fenoprain,Jutanorm,Nistaken,Norfenon,Pintoform,Prolecofen,Propafenon AL,Propafenon Hexal,Propafenon Minden,Propafenone Hydrochloride,Propafenone Hydrochloride, (R)-Isomer,Propafenone Hydrochloride, (S)-Isomer,Propafenone, (+-)-Isomer,Propafenone, (R)-Isomer,Propafenone, (S)-Isomer,Propamerck,Rythmol,Rytmo-Puren,Rytmogenat,Rytmonorm,SA-79,Hydrochloride, Propafenone,SA 79,SA79
D011446 Prospective Studies Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group. Prospective Study,Studies, Prospective,Study, Prospective
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D002675 Child, Preschool A child between the ages of 2 and 5. Children, Preschool,Preschool Child,Preschool Children
D004341 Drug Evaluation Any process by which toxicity, metabolism, absorption, elimination, preferred route of administration, safe dosage range, etc., for a drug or group of drugs is determined through clinical assessment in humans or veterinary animals. Evaluation Studies, Drug,Drug Evaluation Studies,Drug Evaluation Study,Drug Evaluations,Evaluation Study, Drug,Evaluation, Drug,Evaluations, Drug,Studies, Drug Evaluation,Study, Drug Evaluation
D004562 Electrocardiography Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY. 12-Lead ECG,12-Lead EKG,12-Lead Electrocardiography,Cardiography,ECG,EKG,Electrocardiogram,Electrocardiograph,12 Lead ECG,12 Lead EKG,12 Lead Electrocardiography,12-Lead ECGs,12-Lead EKGs,12-Lead Electrocardiographies,Cardiographies,ECG, 12-Lead,EKG, 12-Lead,Electrocardiograms,Electrocardiographies, 12-Lead,Electrocardiographs,Electrocardiography, 12-Lead
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths

Related Publications

A Celiker, and S Ozer, and S Ozme, and S Ozkutlu, and O Kahramanyol
August 1994, European heart journal,
A Celiker, and S Ozer, and S Ozme, and S Ozkutlu, and O Kahramanyol
January 2012, Kardiologiia,
A Celiker, and S Ozer, and S Ozme, and S Ozkutlu, and O Kahramanyol
April 1990, The Medical letter on drugs and therapeutics,
A Celiker, and S Ozer, and S Ozme, and S Ozkutlu, and O Kahramanyol
February 1992, The American journal of the medical sciences,
A Celiker, and S Ozer, and S Ozme, and S Ozkutlu, and O Kahramanyol
December 1988, European heart journal,
A Celiker, and S Ozer, and S Ozme, and S Ozkutlu, and O Kahramanyol
March 1985, Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde,
A Celiker, and S Ozer, and S Ozme, and S Ozkutlu, and O Kahramanyol
January 1995, Drug safety,
A Celiker, and S Ozer, and S Ozme, and S Ozkutlu, and O Kahramanyol
September 1984, Canadian Medical Association journal,
A Celiker, and S Ozer, and S Ozme, and S Ozkutlu, and O Kahramanyol
November 1984, The American journal of cardiology,
A Celiker, and S Ozer, and S Ozme, and S Ozkutlu, and O Kahramanyol
August 1993, The American journal of cardiology,
Copied contents to your clipboard!