[Beta 2-microglobulin in monoclonal gammopathies].
1990
A Anania, and
G Cascio, and
S Rostagno, and
C Ricci
Istituto di Medicina Interna, Università di Torino.
UI
MeSH Term
Description
Entries
D010265
Paraproteinemias
A group of related diseases characterized by an unbalanced or disproportionate proliferation of immunoglobulin-producing cells, usually from a single clone. These cells frequently secrete a structurally homogeneous immunoglobulin (M-component) and/or an abnormal immunoglobulin.
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001613
beta 2-Microglobulin
An 11-kDa protein associated with the outer membrane of many cells including LYMPHOCYTES. It is the small subunit of MHC CLASS I MOLECULES. Association with beta 2-microglobulin is generally required for the transport of class I heavy chains from the endoplasmic reticulum to the cell surface. Beta 2-microglobulin is present in small amounts in serum, CEREBROSPINAL FLUID, and urine of healthy individuals, and to a much greater degree in the urine and plasma of patients with tubular PROTEINURIA, renal failure, or kidney transplants.
Thymotaxin,beta 2 Microglobulin
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A Anania, and
G Cascio, and
S Rostagno, and
C Ricci