Exogenous and endogenous glucocorticoids in rheumatic diseases.
2011
Frank Buttgereit, and
Gerd-Rüdiger Burmester, and
Rainer H Straub, and
Markus J Seibel, and
Hong Zhou
Charité University Medicine Berlin and Berlin-Brandenburg Center of Regenerative Therapies, Berlin, Germany. frank.buttgereit@charite.de
UI
MeSH Term
Description
Entries
D007249
Inflammation
A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system.