Biomaterial Database

[Anti-neutrophil cytoplasmic antibody(ANCA), MPO-ANCA, PR3-ANCA]. 2010

Hajime Takizawa

Fourth Department of Internal Medicine, Teikyo University School of Medicine University Hospital, Mizonokuchi.

UI	MeSH Term	Description	Entries
D009195	Peroxidase	A hemeprotein from leukocytes. Deficiency of this enzyme leads to a hereditary disorder coupled with disseminated moniliasis. It catalyzes the conversion of a donor and peroxide to an oxidized donor and water. EC 1.11.1.7.	Myeloperoxidase,Hemi-Myeloperoxidase,Hemi Myeloperoxidase
D012016	Reference Values	The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.	Normal Range,Normal Values,Reference Ranges,Normal Ranges,Normal Value,Range, Normal,Range, Reference,Ranges, Normal,Ranges, Reference,Reference Range,Reference Value,Value, Normal,Value, Reference,Values, Normal,Values, Reference
D004797	Enzyme-Linked Immunosorbent Assay	An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.	ELISA,Assay, Enzyme-Linked Immunosorbent,Assays, Enzyme-Linked Immunosorbent,Enzyme Linked Immunosorbent Assay,Enzyme-Linked Immunosorbent Assays,Immunosorbent Assay, Enzyme-Linked,Immunosorbent Assays, Enzyme-Linked
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D013048	Specimen Handling	Procedures for collecting, preserving, and transporting of specimens sufficiently stable to provide accurate and precise results suitable for clinical interpretation.	Specimen Collection,Collection, Specimen,Collections, Specimen,Handling, Specimen,Handlings, Specimen,Specimen Collections,Specimen Handlings
D014890	Granulomatosis with Polyangiitis	A multisystemic disease of a complex genetic background. It is characterized by inflammation of the blood vessels (VASCULITIS) leading to damage in any number of organs. The common features include granulomatous inflammation of the RESPIRATORY TRACT and KIDNEYS. Most patients have measurable autoantibodies (ANTINEUTROPHIL CYTOPLASMIC ANTIBODIES) against MYELOBLASTIN.	Granulomatosis, Wegener's,Wegener Granulomatosis,Wegener's Granulomatosis,Granulomatosis with Polyangiitides,Granulomatosis, Wegener,Polyangiitides, Granulomatosis with,Polyangiitis, Granulomatosis with,with Polyangiitides, Granulomatosis,with Polyangiitis, Granulomatosis
D015267	Churg-Strauss Syndrome	Widespread necrotizing angiitis with granulomas. Pulmonary involvement is frequent. Asthma or other respiratory infection may precede evidence of vasculitis. Eosinophilia and lung involvement differentiate this disease from POLYARTERITIS NODOSA.	Allergic Angiitis,Allergic Granulomatous Angiitis,Angiitis, Allergic Granulomatous,EGPA Disorder,Eosinophilic Granulomatosis with Polyangiitis,Vasculitis, Churg-Strauss,Allergic Angiitis and Granulomatosis,Allergic Granulomatosis,Allergic Granulomatous and Angiitis,Eosinophilic Granulomatous Vasculitis,Granulomatous Allergic Angiitis,Allergic Angiitides,Allergic Angiitides, Granulomatous,Allergic Angiitis, Granulomatous,Allergic Granulomatoses,Allergic Granulomatous Angiitides,Angiitides, Allergic,Angiitides, Allergic Granulomatous,Angiitides, Granulomatous Allergic,Angiitis, Allergic,Angiitis, Granulomatous Allergic,Churg Strauss Syndrome,Churg-Strauss Vasculitis,Disorder, EGPA,Disorders, EGPA,EGPA Disorders,Granulomatoses, Allergic,Granulomatosis, Allergic,Granulomatous Allergic Angiitides,Granulomatous Angiitides, Allergic,Granulomatous Angiitis, Allergic,Granulomatous Vasculitides, Eosinophilic,Granulomatous Vasculitis, Eosinophilic,Syndrome, Churg-Strauss,Vasculitides, Eosinophilic Granulomatous,Vasculitis, Churg Strauss,Vasculitis, Eosinophilic Granulomatous
D015415	Biomarkers	Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, ENVIRONMENTAL EXPOSURE and its effects, disease diagnosis; METABOLIC PROCESSES; SUBSTANCE ABUSE; PREGNANCY; cell line development; EPIDEMIOLOGIC STUDIES; etc.	Biochemical Markers,Biological Markers,Biomarker,Clinical Markers,Immunologic Markers,Laboratory Markers,Markers, Biochemical,Markers, Biological,Markers, Clinical,Markers, Immunologic,Markers, Laboratory,Markers, Serum,Markers, Surrogate,Markers, Viral,Serum Markers,Surrogate Markers,Viral Markers,Biochemical Marker,Biologic Marker,Biologic Markers,Clinical Marker,Immune Marker,Immune Markers,Immunologic Marker,Laboratory Marker,Marker, Biochemical,Marker, Biological,Marker, Clinical,Marker, Immunologic,Marker, Laboratory,Marker, Serum,Marker, Surrogate,Serum Marker,Surrogate End Point,Surrogate End Points,Surrogate Endpoint,Surrogate Endpoints,Surrogate Marker,Viral Marker,Biological Marker,End Point, Surrogate,End Points, Surrogate,Endpoint, Surrogate,Endpoints, Surrogate,Marker, Biologic,Marker, Immune,Marker, Viral,Markers, Biologic,Markers, Immune
D053146	Myeloblastin	A polymorphonuclear leukocyte-derived serine protease that degrades proteins such as ELASTIN; FIBRONECTIN; LAMININ; VITRONECTIN; and COLLAGEN. It is named for its ability to control myeloid cell growth and differentiation.	Neutrophil Proteinase 3,Wegener Autoantigen,Azurophil Granule Protein 7,C-ANCA Antigen,Leukocyte Proteinase 3,Myeloblastin, Human,N-Proteinase 4,Neutrophil Proteinase 3, Human,Neutrophil Proteinase 4,PRTN3 Gene Protein,Proteinase 3,Antigen, C-ANCA,Autoantigen, Wegener,C ANCA Antigen,Human Myeloblastin,N Proteinase 4,Protein, PRTN3 Gene,Proteinase 3, Leukocyte,Proteinase 3, Neutrophil,Proteinase 4, Neutrophil
D055953	Microscopic Polyangiitis	A primary systemic vasculitis of small- and some medium-sized vessels. It is characterized by a tropism for kidneys and lungs, positive association with anti-neutrophil cytoplasmic antibodies (ANCA), and a paucity of immunoglobulin deposits in vessel walls.	Microscopic Polyangiitides,Polyangiitides, Microscopic,Polyangiitis, Microscopic