Biomaterial Database

Retrospective study of myocarditis associated with reovirus in turkeys. 2010

M França, and R Crespo, and R Chin, and P Woolcock, and H L Shivaprasad

California Animal Health and Food Safety Laboratory System, Fresno Branch, University of California, Davis, 2789 S. Orange Avenue, Fresno, CA 93725, USA.

The myocarditis associated with reovirus in commercial turkeys was studied retrospectively. Fifty-two cases were identified between 1991 and 2009. The lesions occurred in four different poultry companies in California and affected male and female turkeys with an average age of 19 days. Increased mortality in the turkey flocks ranged from 0.35% to 3% per week in 47 cases. Reovirus was isolated from the heart in 14 out of 19 cases. Twenty-four out of 28 birds from nine cases had low vitamin E levels in the liver ranging from 0.29 to 2.5 ppm (normal 3.0 to > or = 15 ppm). Transmission electron microscopy of the heart revealed degenerative changes in the myocardial cells. Reovirus has been suggested as a probable etiology of this condition. Vitamin E deficiency might also contribute to the development of the lesions.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D009205	Myocarditis	Inflammatory processes of the muscular walls of the heart (MYOCARDIUM) which result in injury to the cardiac muscle cells (MYOCYTES, CARDIAC). Manifestations range from subclinical to sudden death (DEATH, SUDDEN). Myocarditis in association with cardiac dysfunction is classified as inflammatory CARDIOMYOPATHY usually caused by INFECTION, autoimmune diseases, or responses to toxic substances. Myocarditis is also a common cause of DILATED CARDIOMYOPATHY and other cardiomyopathies.	Carditis,Myocarditides
D009206	Myocardium	The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow.	Muscle, Cardiac,Muscle, Heart,Cardiac Muscle,Myocardia,Cardiac Muscles,Heart Muscle,Heart Muscles,Muscles, Cardiac,Muscles, Heart
D011201	Poultry Diseases	Diseases of birds which are raised as a source of meat or eggs for human consumption and are usually found in barnyards, hatcheries, etc. The concept is differentiated from BIRD DISEASES which is for diseases of birds not considered poultry and usually found in zoos, parks, and the wild.	Disease, Poultry,Diseases, Poultry,Poultry Disease
D012088	Reoviridae Infections	Infections produced by reoviruses, general or unspecified.	Reovirus Infections,Infections, Reoviridae,Infection, Reoviridae,Infection, Reovirus,Infections, Reovirus,Reoviridae Infection,Reovirus Infection
D005260	Female		Females
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D012189	Retrospective Studies	Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.	Retrospective Study,Studies, Retrospective,Study, Retrospective
D014422	Turkeys	Large woodland game BIRDS in the subfamily Meleagridinae, family Phasianidae, order GALLIFORMES. Formerly they were considered a distinct family, Melegrididae.	Meleagridinae,Meleagrididae
D030101	Orthoreovirus, Avian	A species of ORTHOREOVIRUS infecting birds, with outcomes ranging from inapparent to lethal depending on the virus strain and age of the host bird. This species does not infect mammals.	Avian Reoviruses,Avian orthoreovirus,Avian Reovirus,Reovirus, Avian,Reoviruses, Avian