Oxygen partial pressure distribution within skeletal muscle: indicator of whole body oxygen delivery in patients? 1990

P Boekstegers, and R Riessen, and W Seyde
Department of Physiology, Med. Univ. Lübeck, FRG.

Simultaneously with determination of cardiac output, the distribution of oxygen partial pressure within biceps muscle was measured during and after open heart surgery in 29 patients. During extracorporeal circulation (ECC) mean muscular oxygen partial pressure (MPO2m) decreased from 25 mmHg to 14 mmHg with an increase of MPO2 values below 5 mmHg from 4% to 20%. Sustained decrease of MPO2m (greater than 1h) did not occur after ECC. Before ECC and in the postoperative period, MPO2m was lineary correlated (r = 0.85) to whole body oxygen delivery (Ox. offer) suggesting that local oxygen delivery within biceps muscle was sufficiently indicated only by systemic parameters of oxygen transport which require determination of cardiac output. Particularly with regard to relative changes, MPO2m might be used for estimation of whole body oxygen offer clinically.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009132 Muscles Contractile tissue that produces movement in animals. Muscle Tissue,Muscle,Muscle Tissues,Tissue, Muscle,Tissues, Muscle
D010100 Oxygen An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. Dioxygen,Oxygen-16,Oxygen 16
D010101 Oxygen Consumption The rate at which oxygen is used by a tissue; microliters of oxygen STPD used per milligram of tissue per hour; the rate at which oxygen enters the blood from alveolar gas, equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body. (Stedman, 25th ed, p346) Consumption, Oxygen,Consumptions, Oxygen,Oxygen Consumptions
D005112 Extracorporeal Circulation Diversion of blood flow through a circuit located outside the body but continuous with the bodily circulation. Circulation, Extracorporeal,Circulations, Extracorporeal,Extracorporeal Circulations
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly

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