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This paper reports that tumor necrosis serum (TNS) containing tumor necrosis factor (TNF) could inhibit Plasmodium falciparum in vitro. TNS was obtained from rabbits given macrophage-activating agent Mycobacterium tuberculosis (BCG) followed by intravenous administration of bacterial endotoxin (LPS). The results showed that TNS dilutions of 1:3, 1:6 and 1:12 could induce disappearance of Plasmodium falciparum (P less than 0.05) after being cultured 6 hours. TNS decreased red blood cell infective rate of the parasites as compared with the control (P less than 0.05) after 12 hours' cultivation. TNS of 1:3 dilution had further effect at 24 hours (P less than 0.05). Morphological observations showed that the growth of schizonts was retarded and abnormal merozoites were found.
Y M Yao, and
G P Hou, and
M Y Wang, and
Z R Cui, and
F Q Cai
July 1987,
Infection and immunity,
Y M Yao, and
G P Hou, and
M Y Wang, and
Z R Cui, and
F Q Cai
November 1993,
Infection and immunity,
Y M Yao, and
G P Hou, and
M Y Wang, and
Z R Cui, and
F Q Cai
September 1990,
Infection and immunity,
Y M Yao, and
G P Hou, and
M Y Wang, and
Z R Cui, and
F Q Cai
December 1988,
Infection and immunity,
Y M Yao, and
G P Hou, and
M Y Wang, and
Z R Cui, and
F Q Cai
October 1983,
Infection and immunity,
Y M Yao, and
G P Hou, and
M Y Wang, and
Z R Cui, and
F Q Cai
March 1990,
Infection and immunity,
Y M Yao, and
G P Hou, and
M Y Wang, and
Z R Cui, and
F Q Cai
January 1988,
Transactions of the Royal Society of Tropical Medicine and Hygiene,
Y M Yao, and
G P Hou, and
M Y Wang, and
Z R Cui, and
F Q Cai
March 1992,
Infection and immunity,
Y M Yao, and
G P Hou, and
M Y Wang, and
Z R Cui, and
F Q Cai
December 1986,
The Journal of parasitology,
Y M Yao, and
G P Hou, and
M Y Wang, and
Z R Cui, and
F Q Cai
August 1989,
The American journal of medicine,
