Biomaterial Database

Thyrotropic exophthalmos. 1946

E M ISBERG

UI	MeSH Term	Description	Entries
D005094	Exophthalmos	Abnormal protrusion of both eyes; may be caused by endocrine gland malfunction, malignancy, injury, or paralysis of the extrinsic muscles of the eye.	Proptosis,Proptoses
D006042	Goiter	Enlargement of the THYROID GLAND that may increase from about 20 grams to hundreds of grams in human adults. Goiter is observed in individuals with normal thyroid function (euthyroidism), thyroid deficiency (HYPOTHYROIDISM), or hormone overproduction (HYPERTHYROIDISM). Goiter may be congenital or acquired, sporadic or endemic (GOITER, ENDEMIC).	Goiters
D006111	Graves Disease	A common form of hyperthyroidism with a diffuse hyperplastic GOITER. It is an autoimmune disorder that produces antibodies against the THYROID STIMULATING HORMONE RECEPTOR. These autoantibodies activate the TSH receptor, thereby stimulating the THYROID GLAND and hypersecretion of THYROID HORMONES. These autoantibodies can also affect the eyes (GRAVES OPHTHALMOPATHY) and the skin (Graves dermopathy).	Basedow's Disease,Exophthalmic Goiter,Goiter, Exophthalmic,Graves' Disease,Basedow Disease,Hyperthyroidism, Autoimmune,Basedows Disease,Disease, Basedow,Disease, Basedow's,Disease, Graves,Disease, Graves',Exophthalmic Goiters,Goiters, Exophthalmic
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D052684	Thyrotrophs	Anterior pituitary cells that produce THYROID-STIMULATING HORMONE.	Pituitary TSH-Secreting Cells,Pituitary TSH-Producing Cells,TSH Cells,Cell, TSH,Pituitary TSH Producing Cells,Pituitary TSH Secreting Cells,Pituitary TSH-Producing Cell,Pituitary TSH-Secreting Cell,TSH Cell,TSH-Producing Cell, Pituitary,TSH-Producing Cells, Pituitary,TSH-Secreting Cell, Pituitary,TSH-Secreting Cells, Pituitary,Thyrotroph