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A Flt3L encounter: mTOR signaling in dendritic cells. 2010

Li Wu
Immunology Division, Walter and Eliza Hall Institute, Melbourne, Parkville Victoria 3052, Australia. wu@wehi.edu.au

The signaling pathway of the cytokine Flt3L in dendritic cells (DCs) is poorly defined. In this issue of Immunity, Sathaliyawala et al. (2010) report that the kinase mTOR functions as a mediator of Flt3L signaling in the development and homeostasis of DCs, particularly of the CD8(+) and CD103(+) DCs.

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