A quantitative study of the interaction of ultraviolet A and ultraviolet B in producing delayed pigmentation. 1990

C H Keong, and Y Kurumaji, and K Nishioka
Department of Dermatology, School of Medicine, Tokyo Medical and Dental University, Japan.

The interaction of ultraviolet A (UVA) and UVB in producing delayed pigmentation was quantitatively studied on the backs of 19 healthy Japanese subjects. The minimal pigementation dose for UVA (MPDA) and UVB (MPDB) was first determined using narrow-band radiation of 360 nm and 290 nm respectively. The average MPDA and MPDB was 16.4 J/cm2 and 32.9 mJ/cm2 respectively. In experiment 1, fractional doses of 0.2, 0.4, 0.6 and 0.8 MPDA were first irradiated on 4 sites each. Immediately following each exposure, fractional doses of either 0.2, 0.4, 0.6 or 0.8 MPDB were superimposed on the same sites, resulting in each exposure site receiving a different combination of fractions of MPDA and MPDB (A + B). This was repeated with the sequence of exposure reversed (B + A). The results demonstrated that the wavelengths interacted via photoaddition in producing delayed pigmentation, irrespective of the order of exposure. When a 3-h time interval was allowed between exposures in experiment 2, there was again no evidence of deviation from photoaddition with either order of exposure. This study shows that subthreshold doses of UVA and UVB interact additively in the production of delayed pigmentation.

UI MeSH Term Description Entries
D008297 Male Males
D004307 Dose-Response Relationship, Radiation The relationship between the dose of administered radiation and the response of the organism or tissue to the radiation. Dose Response Relationship, Radiation,Dose-Response Relationships, Radiation,Radiation Dose-Response Relationship,Radiation Dose-Response Relationships,Relationship, Radiation Dose-Response,Relationships, Radiation Dose-Response
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D012880 Skin Pigmentation Coloration of the skin. Skin Color,Skin Tone,Color, Skin,Colors, Skin,Pigmentation, Skin,Pigmentations, Skin,Skin Colors,Skin Pigmentations,Skin Tones,Tone, Skin,Tones, Skin
D013997 Time Factors Elements of limited time intervals, contributing to particular results or situations. Time Series,Factor, Time,Time Factor
D014466 Ultraviolet Rays That portion of the electromagnetic spectrum immediately below the visible range and extending into the x-ray frequencies. The longer wavelengths (near-UV or biotic or vital rays) are necessary for the endogenous synthesis of vitamin D and are also called antirachitic rays; the shorter, ionizing wavelengths (far-UV or abiotic or extravital rays) are viricidal, bactericidal, mutagenic, and carcinogenic and are used as disinfectants. Actinic Rays,Black Light, Ultraviolet,UV Light,UV Radiation,Ultra-Violet Rays,Ultraviolet Light,Ultraviolet Radiation,Actinic Ray,Light, UV,Light, Ultraviolet,Radiation, UV,Radiation, Ultraviolet,Ray, Actinic,Ray, Ultra-Violet,Ray, Ultraviolet,Ultra Violet Rays,Ultra-Violet Ray,Ultraviolet Black Light,Ultraviolet Black Lights,Ultraviolet Radiations,Ultraviolet Ray

Related Publications

C H Keong, and Y Kurumaji, and K Nishioka
June 1965, Photochemistry and photobiology,
C H Keong, and Y Kurumaji, and K Nishioka
November 1953, The Journal of clinical investigation,
C H Keong, and Y Kurumaji, and K Nishioka
August 2007, Proceedings of the National Academy of Sciences of the United States of America,
C H Keong, and Y Kurumaji, and K Nishioka
June 1996, Photodermatology, photoimmunology & photomedicine,
C H Keong, and Y Kurumaji, and K Nishioka
June 1998, Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete,
C H Keong, and Y Kurumaji, and K Nishioka
February 2002, The Journal of investigative dermatology,
C H Keong, and Y Kurumaji, and K Nishioka
September 2010, The British journal of dermatology,
C H Keong, and Y Kurumaji, and K Nishioka
September 1993, Cancer research,
C H Keong, and Y Kurumaji, and K Nishioka
January 1978, Vision research,
Copied contents to your clipboard!