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After changing over from the usual eating habits to a "reasonable" restricted diet rich in polyene saturated fats and saturated fatty acids, additional treatment with 1 g clofibrate twice daily produces a significant reduction of concentration of total cholesterol and Apo B by about 24% in the serum of patients with Type IIa hyperlipoproteinemia after 2 weeks. In contrast to this the serum concentration of triglycerides and phospholipids shows an insignificant tendency to fall during the whole duration of the trial. The results suggest that the additional cholesterol reducing action of clofibrate in patients with hyperlipoproteinemia Type IIa who have already been treated by diet is mainly achieved by the reduction of LDL-cholesterol, the atherogenic properties of which are well known.
D P Mertz, and
I Suermann, and
E Göhmann
April 1982,
Archives of internal medicine,
D P Mertz, and
I Suermann, and
E Göhmann
December 1978,
Medizinische Klinik,
D P Mertz, and
I Suermann, and
E Göhmann
March 1974,
Deutsche medizinische Wochenschrift (1946),
D P Mertz, and
I Suermann, and
E Göhmann
November 1977,
Pediatriia,
D P Mertz, and
I Suermann, and
E Göhmann
January 1976,
Acta medica Scandinavica,
D P Mertz, and
I Suermann, and
E Göhmann
June 1981,
Metabolism: clinical and experimental,
D P Mertz, and
I Suermann, and
E Göhmann
January 1979,
Acta medica Austriaca,
D P Mertz, and
I Suermann, and
E Göhmann
January 1997,
Terapevticheskii arkhiv,
D P Mertz, and
I Suermann, and
E Göhmann
January 2002,
Indian journal of dermatology, venereology and leprology,
D P Mertz, and
I Suermann, and
E Göhmann
October 1974,
Zeitschrift fur Orthopadie und ihre Grenzgebiete,
