Biomaterial Database

Choroid plexus papilloma of the cerebellopontine angle. 2010

Maliheh Khoddami, and Roohollah Gholampour Shahaboddini

Department of Pathology and Laboratory Medicine, Shaheed Beheshti University of Medical Sciences, Tehran, Iran. malihekhoddami@yahoo.com

The cerebellopontine angle is an extremely rare site for the growth of a choroid plexus papilloma. The clinicoradiological diagnosis of this tumor in the cerebellopontine angle is difficult because of its rarity in addition to a nonspecific clinical presentation and radiological features. Herein, we report the case of a 49-year-old woman with complaints of headache and features of raised intracranial pressure, whose computerized tomography (CT) and magnetic resonance imaging (MRI) were suggestive of acoustic neuroma or meningioma with hydrocephalus. Histology revealed multiple arborizing papillae with a central fibrovascular core, lined by cubo-columnar cells. The cells showed diffuse immunoreactivity for pancytokeratin, S100 protein, synaptophysin, and vimentin, as well as focal expression of glial fibrillary acidic protein, epithelial membrane antigen, and cytokeratin 7. English medical literature is also reviewed.

UI	MeSH Term	Description	Entries
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D002528	Cerebellar Neoplasms	Primary or metastatic neoplasms of the CEREBELLUM. Tumors in this location frequently present with ATAXIA or signs of INTRACRANIAL HYPERTENSION due to obstruction of the fourth ventricle. Common primary cerebellar tumors include fibrillary ASTROCYTOMA and cerebellar HEMANGIOBLASTOMA. The cerebellum is a relatively common site for tumor metastases from the lung, breast, and other distant organs. (From Okazaki & Scheithauer, Atlas of Neuropathology, 1988, p86 and p141)	Benign Cerebellar Neoplasms,Cerebellar Cancer,Malignant Cerebellar Neoplasms,Cerebellar Neoplasms, Benign,Cerebellar Neoplasms, Malignant,Cerebellar Neoplasms, Primary,Cerebellar Tumors,Neoplasms, Cerebellar,Neoplasms, Cerebellar, Benign,Neoplasms, Cerebellar, Malignant,Neoplasms, Cerebellar, Primary,Primary Neoplasms, Cerebellum,Benign Cerebellar Neoplasm,Cancer, Cerebellar,Cerebellar Cancers,Cerebellar Neoplasm,Cerebellar Neoplasm, Benign,Cerebellar Neoplasm, Malignant,Cerebellar Neoplasm, Primary,Cerebellar Tumor,Cerebellum Primary Neoplasm,Cerebellum Primary Neoplasms,Malignant Cerebellar Neoplasm,Neoplasm, Benign Cerebellar,Neoplasm, Cerebellar,Neoplasm, Cerebellum Primary,Neoplasm, Malignant Cerebellar,Primary Cerebellar Neoplasm,Primary Cerebellar Neoplasms,Primary Neoplasm, Cerebellum,Tumor, Cerebellar
D002530	Cerebellopontine Angle	Junction between the cerebellum and the pons.	Cerebellopontile Angle,Angle, Cerebellopontile,Angle, Cerebellopontine,Angles, Cerebellopontile,Angles, Cerebellopontine,Cerebellopontile Angles,Cerebellopontine Angles
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D020288	Papilloma, Choroid Plexus	A usually benign neoplasm that arises from the cuboidal epithelium of the choroid plexus and takes the form of an enlarged CHOROID PLEXUS, which may be associated with oversecretion of CSF. The tumor usually presents in the first decade of life with signs of increased intracranial pressure including HEADACHES; ATAXIA; DIPLOPIA; and alterations of mental status. In children it is most common in the lateral ventricles and in adults it tends to arise in the fourth ventricle. Malignant transformation to choroid plexus carcinomas may rarely occur. (Adams et al., Principles of Neurology, 6th ed, p667; DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2072)	Choroid Plexus Papilloma,Papilloma of Choroid Plexus,Choroid Plexus Papillomas,Papillomas, Choroid Plexus