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The levels of serum somatomedin A were determined in 59 growth retarded Japanese children by a radioreceptor assay. Low levels were found in 10 children with growth hormone (GH) deficiency and 7 children with relative GH deficiency with means of 0.26 +/- 0.48 +/- 0.04 U/ml, respectively. Serum somatomedin A levels in 42 retarded children with normal growth hormone levels were within the range of normal adults, and did not correlate with degree of short stature. Significant increases of somatomedin A after hGH administration were found in children with growth hormone deficiency but not in children with normal growth hormone. These results show that determination of somatomedin A in serum corelates well with the state of growth hormone secretion, and is of great importance in the selection of patients for treatment with human growth hormone.
N Hizuka, and
K Takano, and
K Shizume, and
K Kawai
October 1980,
Nursing mirror,
N Hizuka, and
K Takano, and
K Shizume, and
K Kawai
June 1980,
Pathologie-biologie,
N Hizuka, and
K Takano, and
K Shizume, and
K Kawai
February 1986,
Pediatric research,
N Hizuka, and
K Takano, and
K Shizume, and
K Kawai
June 1980,
Acta endocrinologica,
N Hizuka, and
K Takano, and
K Shizume, and
K Kawai
January 1983,
Biology of the neonate,
N Hizuka, and
K Takano, and
K Shizume, and
K Kawai
March 1982,
Annals of clinical biochemistry,
N Hizuka, and
K Takano, and
K Shizume, and
K Kawai
February 1975,
Acta endocrinologica,
N Hizuka, and
K Takano, and
K Shizume, and
K Kawai
June 1968,
Developmental medicine and child neurology,
N Hizuka, and
K Takano, and
K Shizume, and
K Kawai
December 1967,
The Journal of pediatrics,
N Hizuka, and
K Takano, and
K Shizume, and
K Kawai
October 1984,
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme,
