Distribution of fluoride concentration in the rat's bone. 1990

N Narita, and K Kato, and H Nakagaki, and N Ohno, and Y Kameyama, and J A Weatherell
Department of Preventive Denistry and Dental Public Health, School of Dentistry, Nagoya, Japan.

The present study was undertaken to determine the fluoride distribution profile in the rat femur. Male Wistar rats were divided into four groups and given water containing 0, 25, 50, and 100 ppm of fluoride, respectively, for 10 weeks. The fluoride distribution from the periosteum to the endosteum was determined in each specimen after sampling using the abrasive microsampling technique. In the outer circumferential lamellae, the concentration of fluoride was relatively high in the periosteal layer and then decreased gradually towards its interior. In the haversian and interstitial lamellae, it was lower and roughly constant through the tissue. In the inner circumferential lamellae, it rose again to reach the highest level towards the endosteal surface. Fluoride concentration throughout the cortex increased significantly with increasing intake of fluoride. These increases were especially marked at periosteal and endosteal surfaces.

UI MeSH Term Description Entries
D008297 Male Males
D011919 Rats, Inbred Strains Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations or by parent x offspring matings carried out with certain restrictions. This also includes animals with a long history of closed colony breeding. August Rats,Inbred Rat Strains,Inbred Strain of Rat,Inbred Strain of Rats,Inbred Strains of Rats,Rat, Inbred Strain,August Rat,Inbred Rat Strain,Inbred Strain Rat,Inbred Strain Rats,Inbred Strains Rat,Inbred Strains Rats,Rat Inbred Strain,Rat Inbred Strains,Rat Strain, Inbred,Rat Strains, Inbred,Rat, August,Rat, Inbred Strains,Rats Inbred Strain,Rats Inbred Strains,Rats, August,Rats, Inbred Strain,Strain Rat, Inbred,Strain Rats, Inbred,Strain, Inbred Rat,Strains, Inbred Rat
D001842 Bone and Bones A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principal cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX. Bone Tissue,Bone and Bone,Bone,Bones,Bones and Bone,Bones and Bone Tissue,Bony Apophyses,Bony Apophysis,Condyle,Apophyses, Bony,Apophysis, Bony,Bone Tissues,Condyles,Tissue, Bone,Tissues, Bone
D005269 Femur The longest and largest bone of the skeleton, it is situated between the hip and the knee. Trochanter,Greater Trochanter,Lesser Trochanter,Femurs,Greater Trochanters,Lesser Trochanters,Trochanter, Greater,Trochanter, Lesser,Trochanters,Trochanters, Greater,Trochanters, Lesser
D005459 Fluorides Inorganic salts of hydrofluoric acid, HF, in which the fluorine atom is in the -1 oxidation state. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Sodium and stannous salts are commonly used in dentifrices. Fluoride
D000284 Administration, Oral The giving of drugs, chemicals, or other substances by mouth. Drug Administration, Oral,Administration, Oral Drug,Oral Administration,Oral Drug Administration,Administrations, Oral,Administrations, Oral Drug,Drug Administrations, Oral,Oral Administrations,Oral Drug Administrations
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D051381 Rats The common name for the genus Rattus. Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus

Related Publications

N Narita, and K Kato, and H Nakagaki, and N Ohno, and Y Kameyama, and J A Weatherell
March 1968, Nutrition reviews,
N Narita, and K Kato, and H Nakagaki, and N Ohno, and Y Kameyama, and J A Weatherell
January 1966, Advances in fluorine research and dental caries prevention,
N Narita, and K Kato, and H Nakagaki, and N Ohno, and Y Kameyama, and J A Weatherell
December 1963, ANL,
N Narita, and K Kato, and H Nakagaki, and N Ohno, and Y Kameyama, and J A Weatherell
March 1990, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research,
N Narita, and K Kato, and H Nakagaki, and N Ohno, and Y Kameyama, and J A Weatherell
February 1949, Physiologia comparata et oecologia; an international journal of comparative physiology and ecology,
N Narita, and K Kato, and H Nakagaki, and N Ohno, and Y Kameyama, and J A Weatherell
October 1982, Experientia,
N Narita, and K Kato, and H Nakagaki, and N Ohno, and Y Kameyama, and J A Weatherell
March 1978, Journal of the American Dental Association (1939),
N Narita, and K Kato, and H Nakagaki, and N Ohno, and Y Kameyama, and J A Weatherell
March 1965, Journal of oral therapeutics and pharmacology,
N Narita, and K Kato, and H Nakagaki, and N Ohno, and Y Kameyama, and J A Weatherell
September 1980, Bollettino della Societa italiana di biologia sperimentale,
N Narita, and K Kato, and H Nakagaki, and N Ohno, and Y Kameyama, and J A Weatherell
April 1990, Nihon Ika Daigaku zasshi,
Copied contents to your clipboard!