-transparent.png){kind=logo}
Serum and CSF from 53 vascular dementia (VD) patients and 50 controls were analysed to investigate the possibility of an intrathecal synthesis of IgG, defined as an elevated IgG index (greater than or equal to 7) and/or presence of oligoclonal IgG in cerebrospinal fluid (CSF), but not in serum. Five (9%) patients and no controls exhibited an intrathecal synthesis of IgG. The IgG index increased with the degree of dementia (p less than 0.05). It was positively related to presence/absence of hypertension (p less than 0.05) and correlated positively with diastolic blood pressure (p less than 0.05). The findings suggest that immunological factors might be involved in the pathogenesis of VD.
A Wallin, and
K Blennow, and
P Fredman, and
C G Gottfries, and
I Karlsson, and
L Svennerholm
July 2019,
JAMA neurology,
A Wallin, and
K Blennow, and
P Fredman, and
C G Gottfries, and
I Karlsson, and
L Svennerholm
January 2019,
Neurology India,
A Wallin, and
K Blennow, and
P Fredman, and
C G Gottfries, and
I Karlsson, and
L Svennerholm
January 2000,
Revista de neurologia,
A Wallin, and
K Blennow, and
P Fredman, and
C G Gottfries, and
I Karlsson, and
L Svennerholm
January 2006,
Neuroimmunomodulation,
A Wallin, and
K Blennow, and
P Fredman, and
C G Gottfries, and
I Karlsson, and
L Svennerholm
March 1987,
Clinical and experimental immunology,
A Wallin, and
K Blennow, and
P Fredman, and
C G Gottfries, and
I Karlsson, and
L Svennerholm
August 1992,
Clinical chemistry,
A Wallin, and
K Blennow, and
P Fredman, and
C G Gottfries, and
I Karlsson, and
L Svennerholm
May 1995,
Clinical and diagnostic laboratory immunology,
A Wallin, and
K Blennow, and
P Fredman, and
C G Gottfries, and
I Karlsson, and
L Svennerholm
January 1995,
Medicinski pregled,
A Wallin, and
K Blennow, and
P Fredman, and
C G Gottfries, and
I Karlsson, and
L Svennerholm
December 1997,
Arquivos de neuro-psiquiatria,
A Wallin, and
K Blennow, and
P Fredman, and
C G Gottfries, and
I Karlsson, and
L Svennerholm
January 2004,
Revista de neurologia,
