Stroke due to lyme neuroborreliosis: changes in vessel wall contrast enhancement. 2012

Axel Lebas, and Frédérique Toulgoat, and Guillaume Saliou, and Béatrice Husson, and Marc Tardieu
Assistance Publique-Hôpitaux de Paris, Service de neurologie pédiatrique et Centre de Référence des maladies inflammatoires du cerveau, Hôpital Bicêtre, Le Kremlin-Bicêtre, France. suhailc1000@hotmail.com

OBJECTIVE Neuroborreliosis is a rare cause of stroke in children. We aim here to demonstrate the diagnostic value of gadolinium-enhanced magnetic resonance imaging (MRI) for demonstrating vessel wall abnormality in a child with brainstem stroke. RESULTS We report here the case of an 8-year-old boy with cerebral vasculitis and stroke due to Lyme neuroborreliosis. Imaging studies revealed the presence of ischemic lesions in the pons and cerebellum, with focal stenosis of the basilar artery on magnetic resonance angiography and focal gadolinium enhancement of the basilar artery wall. Nine months after treatment, clinical outcome was favorable, with no enhancement of the basilar artery. CONCLUSIONS Gadolinium-enhanced MRI provided additional information facilitating the diagnosis of vasculitis in a child with Lyme neuroborreliosis and stroke. The location of vessel wall enhancement was correlated with the topography of the acute infarct, and the lack of vessel lumen obstruction supported the diagnosis of vasculitis rather than any other cause.

UI MeSH Term Description Entries
D008279 Magnetic Resonance Imaging Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques. Chemical Shift Imaging,MR Tomography,MRI Scans,MRI, Functional,Magnetic Resonance Image,Magnetic Resonance Imaging, Functional,Magnetization Transfer Contrast Imaging,NMR Imaging,NMR Tomography,Tomography, NMR,Tomography, Proton Spin,fMRI,Functional Magnetic Resonance Imaging,Imaging, Chemical Shift,Proton Spin Tomography,Spin Echo Imaging,Steady-State Free Precession MRI,Tomography, MR,Zeugmatography,Chemical Shift Imagings,Echo Imaging, Spin,Echo Imagings, Spin,Functional MRI,Functional MRIs,Image, Magnetic Resonance,Imaging, Magnetic Resonance,Imaging, NMR,Imaging, Spin Echo,Imagings, Chemical Shift,Imagings, Spin Echo,MRI Scan,MRIs, Functional,Magnetic Resonance Images,Resonance Image, Magnetic,Scan, MRI,Scans, MRI,Shift Imaging, Chemical,Shift Imagings, Chemical,Spin Echo Imagings,Steady State Free Precession MRI
D008297 Male Males
D001921 Brain The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM. Encephalon
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D005682 Gadolinium An element of the rare earth family of metals. It has the atomic symbol Gd, atomic number 64, and atomic weight 157.25. Its oxide is used in the control rods of some nuclear reactors.
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D020293 Vasculitis, Central Nervous System Inflammation of blood vessels within the central nervous system. Primary vasculitis is usually caused by autoimmune or idiopathic factors, while secondary vasculitis is caused by existing disease process. Clinical manifestations are highly variable but include HEADACHE; SEIZURES; behavioral alterations; INTRACRANIAL HEMORRHAGES; TRANSIENT ISCHEMIC ATTACK; and BRAIN INFARCTION. (From Adams et al., Principles of Neurology, 6th ed, pp856-61) Angiitis, Central Nervous System,Central Nervous System Vasculitis,Cerebral Angiitis,Cerebral Vasculitis,Granulomatous Angiitis,Postzoster Arteritis,Primary CNS Vasculitis,Secondary CNS Vasculitis,CNS Vasculitis,Central Nervous System Angiitis,Granulomatous Arteritis,Primary Central Nervous System Vasculitis,Vasculitis, CNS, Secondary,Angiitis, Cerebral,Angiitis, Granulomatous,Arteritis, Granulomatous,Arteritis, Postzoster,CNS Vasculitis, Primary,CNS Vasculitis, Secondary,Vasculitis, CNS,Vasculitis, Cerebral,Vasculitis, Primary CNS,Vasculitis, Secondary CNS
D020521 Stroke A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810) Apoplexy,Cerebral Stroke,Cerebrovascular Accident,Cerebrovascular Apoplexy,Vascular Accident, Brain,CVA (Cerebrovascular Accident),Cerebrovascular Accident, Acute,Cerebrovascular Stroke,Stroke, Acute,Acute Cerebrovascular Accident,Acute Cerebrovascular Accidents,Acute Stroke,Acute Strokes,Apoplexy, Cerebrovascular,Brain Vascular Accident,Brain Vascular Accidents,CVAs (Cerebrovascular Accident),Cerebral Strokes,Cerebrovascular Accidents,Cerebrovascular Accidents, Acute,Cerebrovascular Strokes,Stroke, Cerebral,Stroke, Cerebrovascular,Strokes,Strokes, Acute,Strokes, Cerebral,Strokes, Cerebrovascular,Vascular Accidents, Brain
D020852 Lyme Neuroborreliosis Nervous system infections caused by tick-borne spirochetes of the BORRELIA BURGDORFERI GROUP. The disease may affect elements of the central or peripheral nervous system in isolation or in combination. Common clinical manifestations include a lymphocytic meningitis, cranial neuropathy (most often a facial neuropathy), POLYRADICULOPATHY, and a mild loss of memory and other cognitive functions. Less often more extensive inflammation involving the central nervous system (encephalomyelitis) may occur. In the peripheral nervous system, B. burgdorferi infection is associated with mononeuritis multiplex and polyradiculoneuritis. (From J Neurol Sci 1998 Jan 8;153(2):182-91) Central Nervous System Lyme Disease,Nervous System Lyme Borreliosis,Neuroborreliosis, Borrelia burgdorferi,Peripheral Nervous System Lyme Disease,Encephalopathy, Lyme Disease,Lyme Borreliosis, Nervous System,Lyme Disease Encephalopathy,Lyme Disease Mononeuritis Multiplex,Lyme Disease, Central Nervous System,Lyme Disease, Nervous System,Lyme Meningoencephalitis,Lyme Meningoradiculitis,Lyme Polyradiculitis,Lyme Polyradiculopathy,Meningoencephalitis, Lyme,Mononeuritis Multiplex, Lyme Disease,Nervous System Lyme Disease,Borrelia burgdorferi Neuroborreliosis,Encephalopathies, Lyme Disease,Lyme Disease Encephalopathies,Lyme Polyradiculitides,Lyme Polyradiculopathies,Meningoradiculitis, Lyme,Neuroborrelioses, Borrelia burgdorferi,Neuroborreliosis, Lyme,Polyradiculitides, Lyme,Polyradiculitis, Lyme,Polyradiculopathies, Lyme,Polyradiculopathy, Lyme

Related Publications

Axel Lebas, and Frédérique Toulgoat, and Guillaume Saliou, and Béatrice Husson, and Marc Tardieu
January 2015, Infectious diseases (London, England),
Axel Lebas, and Frédérique Toulgoat, and Guillaume Saliou, and Béatrice Husson, and Marc Tardieu
January 2020, European neurology,
Axel Lebas, and Frédérique Toulgoat, and Guillaume Saliou, and Béatrice Husson, and Marc Tardieu
August 2018, Wiener klinische Wochenschrift,
Axel Lebas, and Frédérique Toulgoat, and Guillaume Saliou, and Béatrice Husson, and Marc Tardieu
September 2023, Rinsho shinkeigaku = Clinical neurology,
Axel Lebas, and Frédérique Toulgoat, and Guillaume Saliou, and Béatrice Husson, and Marc Tardieu
February 2019, Revue des maladies respiratoires,
Axel Lebas, and Frédérique Toulgoat, and Guillaume Saliou, and Béatrice Husson, and Marc Tardieu
February 2002, Neuropediatrics,
Axel Lebas, and Frédérique Toulgoat, and Guillaume Saliou, and Béatrice Husson, and Marc Tardieu
April 2000, Archives of physical medicine and rehabilitation,
Axel Lebas, and Frédérique Toulgoat, and Guillaume Saliou, and Béatrice Husson, and Marc Tardieu
January 2018, Case reports in neurological medicine,
Axel Lebas, and Frédérique Toulgoat, and Guillaume Saliou, and Béatrice Husson, and Marc Tardieu
March 2003, Revue neurologique,
Axel Lebas, and Frédérique Toulgoat, and Guillaume Saliou, and Béatrice Husson, and Marc Tardieu
November 2020, Ticks and tick-borne diseases,
Copied contents to your clipboard!