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The case of a 14-year-old girl with hirsutism and virilism due to the secretion of ectopic ACTH by an adrenal medullary tumor is described. At the age of 5 years changes in appearance had begun with masculinization. The effect of ACTH-like material, measured by radioimmunoassay in plasma and in tumor tissue, was compensated partially by the hypothalamo-pituitary-adrenal feedback mechanism. Increased concentrations of dehydroepiandrosterone, estrone and testosterone in plasma and of 17-ketosteroids and free cortisol in urine originated in the adrenals. After operation of the tumor menarche began spontaneously, hirsutism disappeared and testosterone plasma concentrations returned to normal. An adrenogenital syndrome was excluded.
H K Kley, and
M H Blessing, and
E Nieschlag, and
W Wiegelmann, and
H G Solbach, and
H L Krüskemper
January 1982,
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine,
H K Kley, and
M H Blessing, and
E Nieschlag, and
W Wiegelmann, and
H G Solbach, and
H L Krüskemper
November 1977,
Nihon Naibunpi Gakkai zasshi,
H K Kley, and
M H Blessing, and
E Nieschlag, and
W Wiegelmann, and
H G Solbach, and
H L Krüskemper
March 1979,
Medicina clinica,
H K Kley, and
M H Blessing, and
E Nieschlag, and
W Wiegelmann, and
H G Solbach, and
H L Krüskemper
December 1980,
Australian and New Zealand journal of medicine,
H K Kley, and
M H Blessing, and
E Nieschlag, and
W Wiegelmann, and
H G Solbach, and
H L Krüskemper
May 1975,
Deutsche medizinische Wochenschrift (1946),
H K Kley, and
M H Blessing, and
E Nieschlag, and
W Wiegelmann, and
H G Solbach, and
H L Krüskemper
May 1976,
Revista medica de Chile,
H K Kley, and
M H Blessing, and
E Nieschlag, and
W Wiegelmann, and
H G Solbach, and
H L Krüskemper
July 1988,
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme,
H K Kley, and
M H Blessing, and
E Nieschlag, and
W Wiegelmann, and
H G Solbach, and
H L Krüskemper
October 2008,
Cirugia espanola,
H K Kley, and
M H Blessing, and
E Nieschlag, and
W Wiegelmann, and
H G Solbach, and
H L Krüskemper
September 1980,
Horumon to rinsho. Clinical endocrinology,
H K Kley, and
M H Blessing, and
E Nieschlag, and
W Wiegelmann, and
H G Solbach, and
H L Krüskemper
September 1994,
Digestive diseases and sciences,
