[Study on the speciation of calcium in Baihu decoction]. 2010

Pei Lü, and Xiang Li, and Jian-wei Chen
College of Pharmacy, Nanjing University of Traditional Chinese Medicine, Nanjing 210046, China. sanshanxiansheng@163.com

A method for speciation analysis of calcium in Baihu decoction was presented. The six different forms of Ca in the filtrate including free ions, non-free ions, exchangeable, non-exchangeable, organic and inorganic were separated by using ion-exchange resin (IER), chelating resin and organic solvent extraction. Various forms of Ca were determined by inductively coupled plasma atomic emission spectrometry (ICP-AES). The recovery for the method is 90.0%-110.0%. The result showed that baihu decoction extract was a kind of complex solution, in which 83.25% of Ca existed in free ions form and 23.79% of Ca existed in organic form in the soluble filtrate.

UI MeSH Term Description Entries
D007477 Ions An atom or group of atoms that have a positive or negative electric charge due to a gain (negative charge) or loss (positive charge) of one or more electrons. Atoms with a positive charge are known as CATIONS; those with a negative charge are ANIONS.
D002118 Calcium A basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes. Coagulation Factor IV,Factor IV,Blood Coagulation Factor IV,Calcium-40,Calcium 40,Factor IV, Coagulation
D002614 Chelating Agents Chemicals that bind to and remove ions from solutions. Many chelating agents function through the formation of COORDINATION COMPLEXES with METALS. Chelating Agent,Chelator,Complexons,Metal Antagonists,Chelators,Metal Chelating Agents,Agent, Chelating,Agents, Chelating,Agents, Metal Chelating,Antagonists, Metal,Chelating Agents, Metal
D004365 Drugs, Chinese Herbal Chinese herbal or plant extracts which are used as drugs to treat diseases or promote general well-being. The concept does not include synthesized compounds manufactured in China. Chinese Herbal Drugs,Plant Extracts, Chinese,Chinese Drugs, Plant,Chinese Plant Extracts,Extracts, Chinese Plant,Herbal Drugs, Chinese
D013057 Spectrum Analysis The measurement of the amplitude of the components of a complex waveform throughout the frequency range of the waveform. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed) Spectroscopy,Analysis, Spectrum,Spectrometry

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