Biomaterial Database

Mutagenic potential of permethrin in the Drosophila melanogaster (Diptera: Drosophilidae) sex-linked recessive lethal test. 1990

R K Gupta, and Z A Mehr, and D W Korte, and L C Rutledge

Letterman Army Institute of Research, Presidio of San Francisco, California 94129.

When permethrin was tested for mutagenicity in Drosophila melanogaster Meigen with the sex-linked recessive lethal test, it was nonmutagenic under conditions of this study. The frequencies of spontaneous mutation for permethrin and the negative control were 0.135% and 0.133%, respectively; the spontaneous mutation frequency for positive control was 12.6%. The difference between the mutation frequency of permethrin and the negative control was not significant.

UI	MeSH Term	Description	Entries
D007306	Insecticides	Pesticides designed to control insects that are harmful to man. The insects may be directly harmful, as those acting as disease vectors, or indirectly harmful, as destroyers of crops, food products, or textile fabrics.	Insecticide
D008297	Male		Males
D009152	Mutagenicity Tests	Tests of chemical substances and physical agents for mutagenic potential. They include microbial, insect, mammalian cell, and whole animal tests.	Genetic Toxicity Tests,Genotoxicity Tests,Mutagen Screening,Tests, Genetic Toxicity,Toxicity Tests, Genetic,Genetic Toxicity Test,Genotoxicity Test,Mutagen Screenings,Mutagenicity Test,Screening, Mutagen,Screenings, Mutagen,Test, Genotoxicity,Tests, Genotoxicity,Toxicity Test, Genetic
D009154	Mutation	Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.	Mutations
D011722	Pyrethrins	The active insecticidal constituent of CHRYSANTHEMUM CINERARIIFOLIUM flowers. Pyrethrin I is the pyretholone ester of chrysanthemummonocarboxylic acid and pyrethrin II is the pyretholone ester of chrysanthemumdicarboxylic acid monomethyl ester.	Pyrethrin,Pyrethroid,Pyrethroids
D004331	Drosophila melanogaster	A species of fruit fly frequently used in genetics because of the large size of its chromosomes.	D. melanogaster,Drosophila melanogasters,melanogaster, Drosophila
D005260	Female		Females
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D026023	Permethrin	A pyrethroid insecticide commonly used in the treatment of LICE INFESTATIONS and SCABIES.	Cyclopropanecarboxylic Acid, 3-(2,2-dichloroethenyl)-2,2-dimethyl-, (3-phenoxyphenyl)methyl ester,(m-Phenoxybenzyl)-cis,trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate,3-Phenoxybenzyl-(+-)-cis,trans-2,2-dichlorovinyl-2,2-dimethyl-cyclopropylcarboxylic acid, ester,3-Phenoxybenzyl-cis,trans-(1RS)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate,Ambush,Elimite,FMC-33297,NIA-33297,NRDC-143,NRDC-147,Nittifor,PP-557,Permethrin, (1R-cis)-Isomer,Permethrin, (1R-trans)-Isomer,Permethrin, (1S-cis)-Isomer,Permethrin, (1S-trans)-Isomer,Permethrin, (cis)-Isomer,Permethrin, (cis-(+-))-Isomer,Permethrin, (trans)-Isomer,Permethrin, (trans-(+-))-Isomer,Permethrin, trans-(1RS)-Isomer,S-3151,cis-(1RS)-permethrin,cis-permethrin,permethrin, cis-(1RS)-isomer,trans-(1RS)-Permethrin,trans-permethrin,FMC 33297,FMC33297,NIA 33297,NIA33297,NRDC 143,NRDC 147,NRDC143,NRDC147,PP 557,PP557,S 3151,S3151,cis permethrin,trans permethrin