-transparent.png){kind=logo}
A prenatal diagnosis for fetal disease was performed at 20 weeks gestation in a severely affected patient with type IIA von Willebrand disease. In the fetal cord blood sample obtained under ultrasound guidance, the level of von Willebrand ristocetin cofactor activity was similar to that of von Willebrand factor antigen, and all the multimers were present. These results were compared to those obtained in 51 normal fetuses of similar gestational age (19-21 weeks). Normal fetuses showed slightly lower levels of von Willebrand factor than normal adults and in addition to all adult multimers, the presence of unusual large forms. This data compared with the case, allowed the exclusion of the diagnosis of type IIA von Willebrand disease in our patient's fetus. This was confirmed at birth in the cord blood.
C Rothschild, and
F Forestier, and
F Daffos, and
Y Sole, and
F Bridey, and
D Meyer, and
M J Larrieu
March 1994,
Annals of hematology,
C Rothschild, and
F Forestier, and
F Daffos, and
Y Sole, and
F Bridey, and
D Meyer, and
M J Larrieu
January 1991,
Annals of the New York Academy of Sciences,
C Rothschild, and
F Forestier, and
F Daffos, and
Y Sole, and
F Bridey, and
D Meyer, and
M J Larrieu
May 1987,
Blood,
C Rothschild, and
F Forestier, and
F Daffos, and
Y Sole, and
F Bridey, and
D Meyer, and
M J Larrieu
November 1992,
The Journal of biological chemistry,
C Rothschild, and
F Forestier, and
F Daffos, and
Y Sole, and
F Bridey, and
D Meyer, and
M J Larrieu
January 2005,
The National medical journal of India,
C Rothschild, and
F Forestier, and
F Daffos, and
Y Sole, and
F Bridey, and
D Meyer, and
M J Larrieu
December 1988,
Thrombosis and haemostasis,
C Rothschild, and
F Forestier, and
F Daffos, and
Y Sole, and
F Bridey, and
D Meyer, and
M J Larrieu
March 1994,
Blood,
C Rothschild, and
F Forestier, and
F Daffos, and
Y Sole, and
F Bridey, and
D Meyer, and
M J Larrieu
March 2006,
The Annals of thoracic surgery,
C Rothschild, and
F Forestier, and
F Daffos, and
Y Sole, and
F Bridey, and
D Meyer, and
M J Larrieu
July 1992,
British journal of haematology,
C Rothschild, and
F Forestier, and
F Daffos, and
Y Sole, and
F Bridey, and
D Meyer, and
M J Larrieu
September 1987,
Proceedings of the National Academy of Sciences of the United States of America,
