| D008074 |
Lipoproteins |
Lipid-protein complexes involved in the transportation and metabolism of lipids in the body. They are spherical particles consisting of a hydrophobic core of TRIGLYCERIDES and CHOLESTEROL ESTERS surrounded by a layer of hydrophilic free CHOLESTEROL; PHOSPHOLIPIDS; and APOLIPOPROTEINS. Lipoproteins are classified by their varying buoyant density and sizes. |
Circulating Lipoproteins,Lipoprotein,Lipoproteins, Circulating |
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| D008077 |
Lipoproteins, LDL |
A class of lipoproteins of small size (18-25 nm) and light (1.019-1.063 g/ml) particles with a core composed mainly of CHOLESTEROL ESTERS and smaller amounts of TRIGLYCERIDES. The surface monolayer consists mostly of PHOSPHOLIPIDS, a single copy of APOLIPOPROTEIN B-100, and free cholesterol molecules. The main LDL function is to transport cholesterol and cholesterol esters to extrahepatic tissues. |
Low-Density Lipoprotein,Low-Density Lipoproteins,beta-Lipoprotein,beta-Lipoproteins,LDL(1),LDL(2),LDL-1,LDL-2,LDL1,LDL2,Low-Density Lipoprotein 1,Low-Density Lipoprotein 2,LDL Lipoproteins,Lipoprotein, Low-Density,Lipoproteins, Low-Density,Low Density Lipoprotein,Low Density Lipoprotein 1,Low Density Lipoprotein 2,Low Density Lipoproteins,beta Lipoprotein,beta Lipoproteins |
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| D008264 |
Macrophages |
The relatively long-lived phagocytic cell of mammalian tissues that are derived from blood MONOCYTES. Main types are PERITONEAL MACROPHAGES; ALVEOLAR MACROPHAGES; HISTIOCYTES; KUPFFER CELLS of the liver; and OSTEOCLASTS. They may further differentiate within chronic inflammatory lesions to EPITHELIOID CELLS or may fuse to form FOREIGN BODY GIANT CELLS or LANGHANS GIANT CELLS. (from The Dictionary of Cell Biology, Lackie and Dow, 3rd ed.) |
Bone Marrow-Derived Macrophages,Monocyte-Derived Macrophages,Macrophage,Macrophages, Monocyte-Derived,Bone Marrow Derived Macrophages,Bone Marrow-Derived Macrophage,Macrophage, Bone Marrow-Derived,Macrophage, Monocyte-Derived,Macrophages, Bone Marrow-Derived,Macrophages, Monocyte Derived,Monocyte Derived Macrophages,Monocyte-Derived Macrophage |
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| D002478 |
Cells, Cultured |
Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others. |
Cultured Cells,Cell, Cultured,Cultured Cell |
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| D002784 |
Cholesterol |
The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils. |
Epicholesterol |
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| D005487 |
Foam Cells |
Lipid-laden macrophages originating from monocytes or from smooth muscle cells. |
Cell, Foam,Cells, Foam,Foam Cell |
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| D000070998 |
ATP Binding Cassette Transporter, Subfamily G, Member 1 |
ATP binding cassette transporter that functions primarily as a lipid and CHOLESTEROL exporter in MACROPHAGES. It may also function in intracellular lipid transport and homoeostasis. |
ABCG1 Protein,ABCG1 Transporter,ATP Binding Cassette Transporter, Sub-Family G, Member 1,ATP-Binding Cassette Transporter 8,White Protein Homolog,ATP Binding Cassette Transporter 8 |
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| D000818 |
Animals |
Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. |
Animal,Metazoa,Animalia |
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| D044950 |
Flavanones |
A group of FLAVONOIDS characterized with a 4-ketone. |
2-Phenyl-Benzopyran-4-Ones,2 Phenyl Benzopyran 4 Ones |
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| D051117 |
Scavenger Receptors, Class A |
A family of scavenger receptors that mediate the influx of LIPIDS into MACROPHAGES and are involved in FOAM CELL formation. |
Macrophage Type-I Class-A Scavenger Receptor,Macrophage Type-II Class-A Scavenger Receptor,SR-A Proteins,SR-AI Protein,SR-AI-II Receptors,SR-AII Protein,Scavenger Receptor Class A Type I-II,Scavenger Receptors, Class A, Type I,Scavenger Receptors, Class A, Type I-II,Scavenger Receptors, Class A, Type II |
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