BIOMAT Database Logo BIOMAT Database Logo

Life-threatening anaphylactic reaction after the administration of airway topical lidocaine. 2011

Wen-Jue Soong, and Yu-Sheng Lee, and Yen-Hui Soong, and Pei-Chen Tsao, and Chia-Feng Yang, and Mei-Ji Jeng, and Yu-Yun Peng
Department of Pediatrics, Children's Medical Center, Taipei Veterans General Hospital, Taiwan, ROC.; Department of Pediatrics, School of Medicine, Institute of Emergency and Critical Care Medicines, National Yang-Ming University, Taipei, Taiwan, ROC.. wjsoong@vghtpe.gov.tw.

A 9-year-old boy who developed a life-threatening anaphylaxis reaction of the airway and subsequent dyspnea and circulation collapse because of instilled the topical lidocaine into the airway within 2 min before performing flexible bronchoscopy (FB). FB revealed swollen airway mucosa and extensive foamy secretion that severely compromised the ventilation lumen. Rapid detection with FB and immediate resuscitation, including prompt administration of epinephrine, volume expander, and positive pressure ventilation with pure oxygen via an endotracheal tube, were successfully save the patient's life.

UI MeSH Term Description Entries
D008012 Lidocaine A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE. Lignocaine,2-(Diethylamino)-N-(2,6-Dimethylphenyl)Acetamide,2-2EtN-2MePhAcN,Dalcaine,Lidocaine Carbonate,Lidocaine Carbonate (2:1),Lidocaine Hydrocarbonate,Lidocaine Hydrochloride,Lidocaine Monoacetate,Lidocaine Monohydrochloride,Lidocaine Monohydrochloride, Monohydrate,Lidocaine Sulfate (1:1),Octocaine,Xylesthesin,Xylocaine,Xylocitin,Xyloneural
D008297 Male Males
D001999 Bronchoscopy Endoscopic examination, therapy or surgery of the bronchi. Bronchoscopic Surgical Procedures,Surgical Procedures, Bronchoscopic,Bronchoscopic Surgery,Surgery, Bronchoscopic,Bronchoscopic Surgeries,Bronchoscopic Surgical Procedure,Bronchoscopies,Surgeries, Bronchoscopic,Surgical Procedure, Bronchoscopic
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D004417 Dyspnea Difficult or labored breathing. Orthopnea,Platypnea,Recumbent Dyspnea,Rest Dyspnea,Trepopnea,Breathlessness,Shortness of Breath,Breath Shortness,Dyspnea, Recumbent,Dyspnea, Rest,Dyspneas, Rest
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000287 Administration, Topical The application of drug preparations to the surfaces of the body, especially the skin (ADMINISTRATION, CUTANEOUS) or mucous membranes. This method of treatment is used to avoid systemic side effects when high doses are required at a localized area or as an alternative systemic administration route, to avoid hepatic processing for example. Drug Administration, Topical,Administration, Topical Drug,Topical Administration,Topical Drug Administration,Administrations, Topical,Administrations, Topical Drug,Drug Administrations, Topical,Topical Administrations,Topical Drug Administrations
D000707 Anaphylaxis An acute hypersensitivity reaction due to exposure to a previously encountered ANTIGEN. The reaction may include rapidly progressing URTICARIA, respiratory distress, vascular collapse, systemic SHOCK, and death. Anaphylactic Reaction,Anaphylactoid Reaction,Anaphylactoid Shock,Shock, Anaphylactic,Anaphylactic Reactions,Anaphylactic Shock,Anaphylactoid Reactions,Reaction, Anaphylactic,Reaction, Anaphylactoid,Shock, Anaphylactoid
D000779 Anesthetics, Local Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate. Anesthetics, Conduction-Blocking,Conduction-Blocking Anesthetics,Local Anesthetic,Anesthetics, Topical,Anesthetic, Local,Anesthetics, Conduction Blocking,Conduction Blocking Anesthetics,Local Anesthetics,Topical Anesthetics
D012769 Shock A pathological condition manifested by failure to perfuse or oxygenate vital organs. Circulatory Collapse,Circulatory Failure,Hypovolemic Shock,Collapse, Circulatory,Failure, Circulatory,Shock, Hypovolemic

Related Publications

Wen-Jue Soong, and Yu-Sheng Lee, and Yen-Hui Soong, and Pei-Chen Tsao, and Chia-Feng Yang, and Mei-Ji Jeng, and Yu-Yun Peng
Systemic anaphylactic reaction following lidocaine administration.
December 1985, Gastrointestinal endoscopy,
Wen-Jue Soong, and Yu-Sheng Lee, and Yen-Hui Soong, and Pei-Chen Tsao, and Chia-Feng Yang, and Mei-Ji Jeng, and Yu-Yun Peng
[Anaphylactic shock after lidocaine administration].
January 1989, Sudebno-meditsinskaia ekspertiza,
Wen-Jue Soong, and Yu-Sheng Lee, and Yen-Hui Soong, and Pei-Chen Tsao, and Chia-Feng Yang, and Mei-Ji Jeng, and Yu-Yun Peng
[A life-threatening anaphylactic reaction following mannitol].
March 1992, Der Anaesthesist,
Wen-Jue Soong, and Yu-Sheng Lee, and Yen-Hui Soong, and Pei-Chen Tsao, and Chia-Feng Yang, and Mei-Ji Jeng, and Yu-Yun Peng
Life-threatening anaphylactic reaction to tetanus toxoid.
August 1982, Annals of allergy,
Wen-Jue Soong, and Yu-Sheng Lee, and Yen-Hui Soong, and Pei-Chen Tsao, and Chia-Feng Yang, and Mei-Ji Jeng, and Yu-Yun Peng
Anaphylactic reaction following administration of topical eyedrops.
July 2021, CJEM,
Wen-Jue Soong, and Yu-Sheng Lee, and Yen-Hui Soong, and Pei-Chen Tsao, and Chia-Feng Yang, and Mei-Ji Jeng, and Yu-Yun Peng
Severe anaphylactic reaction to topical administration of framycetin.
September 1995, The Journal of allergy and clinical immunology,
Wen-Jue Soong, and Yu-Sheng Lee, and Yen-Hui Soong, and Pei-Chen Tsao, and Chia-Feng Yang, and Mei-Ji Jeng, and Yu-Yun Peng
Anaphylactic reaction to lidocaine.
March 1999, Australian dental journal,
Wen-Jue Soong, and Yu-Sheng Lee, and Yen-Hui Soong, and Pei-Chen Tsao, and Chia-Feng Yang, and Mei-Ji Jeng, and Yu-Yun Peng
Anaphylactic reaction to lidocaine.
June 1986, Archives of otolaryngology--head & neck surgery,
Wen-Jue Soong, and Yu-Sheng Lee, and Yen-Hui Soong, and Pei-Chen Tsao, and Chia-Feng Yang, and Mei-Ji Jeng, and Yu-Yun Peng
Anaphylactic reaction after cisatracurium administration.
September 2002, European journal of anaesthesiology,
Wen-Jue Soong, and Yu-Sheng Lee, and Yen-Hui Soong, and Pei-Chen Tsao, and Chia-Feng Yang, and Mei-Ji Jeng, and Yu-Yun Peng
Life-Threatening Reaction with Topical 5-Fluorouracil.
January 2018, Drug safety - case reports,
Copied contents to your clipboard!