Ethyl 3-(4-fluoro-phen-yl)-6-methyl-4-oxo-2-(1-cyclohexylamino)-3,4-dihydro-furo[2,3-d]pyrimidine-5-carboxyl-ate. 2007

Yong Sun, and Guo-Ping Zeng, and Yang-Gen Hu

In the crystal structure of the title compound, C(22)H(24)FN(3)O(4), the two fused rings of furo[2,3-d]pyrimidine form a dihedral angle of 0.88 (13)°. The attached benzene ring is twisted with respect to the heterocyclic pyrimidinone ring, making a dihedral angle of 75.07 (12)°. The cyclo-hexyl ring shows a distorted chair conformation. The mol-ecular structure is stabilized by intra-molecular C-H⋯O and C-H⋯N hydrogen-bonding inter-actions. The crystal packing is mainly stabilized by C-H⋯π hydrogen-bond inter-actions. Further stability is provided by C-F⋯π and C-O⋯π stacking inter-actions.

UI MeSH Term Description Entries

Related Publications

Yong Sun, and Guo-Ping Zeng, and Yang-Gen Hu
August 2009, Acta crystallographica. Section E, Structure reports online,
Yong Sun, and Guo-Ping Zeng, and Yang-Gen Hu
November 2009, Acta crystallographica. Section E, Structure reports online,
Yong Sun, and Guo-Ping Zeng, and Yang-Gen Hu
November 2010, Acta crystallographica. Section E, Structure reports online,
Yong Sun, and Guo-Ping Zeng, and Yang-Gen Hu
January 2016, Acta crystallographica. Section E, Crystallographic communications,
Yong Sun, and Guo-Ping Zeng, and Yang-Gen Hu
November 2013, Acta crystallographica. Section E, Structure reports online,
Yong Sun, and Guo-Ping Zeng, and Yang-Gen Hu
May 2009, Acta crystallographica. Section E, Structure reports online,
Yong Sun, and Guo-Ping Zeng, and Yang-Gen Hu
November 2008, Acta crystallographica. Section E, Structure reports online,
Yong Sun, and Guo-Ping Zeng, and Yang-Gen Hu
September 2009, Acta crystallographica. Section E, Structure reports online,
Yong Sun, and Guo-Ping Zeng, and Yang-Gen Hu
March 2012, Acta crystallographica. Section E, Structure reports online,
Yong Sun, and Guo-Ping Zeng, and Yang-Gen Hu
July 2008, Acta crystallographica. Section E, Structure reports online,
Copied contents to your clipboard!