Ethyl 6-methyl-2-oxo-4-phenyl-1,2,3,4-tetra-hydro-pyrimidine-5-carboxyl-ate. 2008

M Nizam Mohideen, and A Rasheeth, and C A M A Huq, and S Syed Nizar

The title compound, C(14)H(16)N(2)O(3), belongs to a group of esters of 2-oxo- and 1,2,3,4-tetra-hydro-pyrimidine-5-carboxylic acids, which exhibit a wide spectrum of biological activities. The dihydro-pyrimidine ring adopts a screw-boat conformation. The crystal packing is stabilized by strong N-H⋯O and weak C-H⋯O inter-molecular hydrogen bonds. An intra-molecular C-H⋯O hydrogen bond is also present.

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