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Cytophotometric DNA determination was performed on 23 biopsies of meningiomas. The DNA distributions were compared with the histological criteria of malignancy used by the World Health Organisation. Most of the meningiomas studied were diploid or slightly hyperdiploid. In one case, in which eight recurrent tumours were studied, regional differences in histology and DNA pattern were found. Histological anaplasia should be suspected in advance. When it is present, a considerable risk exists that the tumour will recur.
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