Verb production during action naming in semantic dementia. 2011

D Méligne, and M Fossard, and S Belliard, and O Moreaud, and K Duvignau, and J-F Démonet
Inserm, Imagerie cérébrale et handicaps neurologiques UMR 825, F-31059 Toulouse, France. deborah.meligne@inserm.fr

In contrast with widely documented deficits of semantic knowledge relating to object concepts and the corresponding nouns in semantic dementia (SD), little is known about action semantics and verb production in SD. The degradation of action semantic knowledge was studied in 5 patients with SD compared with 17 matched control participants in an action naming task based on video clips. The pattern of errors, involving a huge proportion of generic verbs (e.g. "to remove" versus "to peel") relative to responses in control subjects, suggested a hierarchical, bottom-up deficit of action knowledge in SD patients. In addition, abnormal responses in patients consisted of verbs that were semantically related to the expected verbs produced by control subjects (e.g. "to undress" versus "to peel" for the action [To peel_orange]). This study suggests that, in SD, non-canonical responses to action naming reflect lack of both specificity and semantic relatedness relative to the expected responses. OBJECTIVE As a result of this activity, readers will recognize that semantic word knowledge disappears in semantic dementia using video clips of object-related actions. As a result of this activity, readers will discover that this semantic impairment followed a hierarchical pattern with the more specific verbs vanishing first.

UI MeSH Term Description Entries
D007807 Language Tests Tests designed to assess language behavior and abilities. They include tests of vocabulary, comprehension, grammar and functional use of language, e.g., Development Sentence Scoring, Receptive-Expressive Emergent Language Scale, Parsons Language Sample, Utah Test of Language Development, Michigan Language Inventory and Verbal Language Development Scale, Illinois Test of Psycholinguistic Abilities, Northwestern Syntax Screening Test, Peabody Picture Vocabulary Test, Ammons Full-Range Picture Vocabulary Test, and Assessment of Children's Language Comprehension. Language Comprehension Tests,Vocabulary Tests,Boston Diagnostic Aphasia Examination,Boston Naming Test,Comprehensive Aphasia Test,Multilingual Aphasia Examination,Language Test
D008297 Male Males
D008609 Mental Status Schedule Standardized clinical interview used to assess current psychopathology by scaling patient responses to the questions.
D010364 Pattern Recognition, Visual Mental process to visually perceive a critical number of facts (the pattern), such as characters, shapes, displays, or designs. Recognition, Visual Pattern,Visual Pattern Recognition
D011578 Psycholinguistics A discipline concerned with relations between messages and the characteristics of individuals who select and interpret them; it deals directly with the processes of encoding (phonetics) and decoding (psychoacoustics) as they relate states of messages to states of communicators. Psycholinguistic
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly
D000849 Anomia A language dysfunction characterized by the inability to name people and objects that are correctly perceived. The individual is able to describe the object in question, but cannot provide the name. This condition is associated with lesions of the dominant hemisphere involving the language areas, in particular the TEMPORAL LOBE. (From Adams et al., Principles of Neurology, 6th ed, p484) Aphasia, Amnesic,Aphasia, Anomic,Aphasia, Nominal,Color Anomia,Dysnomia,Anomic Dysphasia,Nominal Dysphasia,Amnesic Aphasia,Anomia, Color,Anomias, Color,Anomic Aphasia,Anomic Dysphasias,Color Anomias,Dysnomias,Dysphasia, Anomic,Dysphasia, Nominal,Dysphasias, Anomic,Dysphasias, Nominal,Nominal Aphasia,Nominal Dysphasias
D012660 Semantics The relationships between symbols and their meanings. Semantic

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