-transparent.png){kind=logo}
Thiazolidione derivatives as novel antibiofilm agents: design, synthesis, biological evaluation, and structure-activity relationships. 2011
Bin Pan, and
Renzheng Huang, and
Likang Zheng, and
Chen Chen, and
Shiqing Han, and
Di Qu, and
Mingli Zhu, and
Ping Wei
College of Biotechnology and Pharmaceutical Engineering, Nanjing University of Technology, Nanjing 210009, China.
Rational designed novel thiazolidiones were synthesized and evaluated for antibiofilm activity. The active derivatives were not only potent inhibitors of Staphylococcus epidermidis biofilm growth but also efficient antibacterial agents. 3f showed 4-fold higher activity (6.25 μM) in the biofilms dispersal assay and significantly higher antibacterial activity (MIC 3.125 μM) in comparison to the 3-(5-((6- (ethoxycarbonyl)-5-(benzo[1,3]dioxol-5-yl)-3-oxo-7-phenyl- thiazolo[3,2-a]pyrimidin-2(5H)-ylidene)methyl)furan-2-yl)benzoic acid (1).
Related Publications
Bin Pan, and
Renzheng Huang, and
Likang Zheng, and
Chen Chen, and
Shiqing Han, and
Di Qu, and
Mingli Zhu, and
Ping Wei
May 2015,
Organic & biomolecular chemistry,
Bin Pan, and
Renzheng Huang, and
Likang Zheng, and
Chen Chen, and
Shiqing Han, and
Di Qu, and
Mingli Zhu, and
Ping Wei
April 1985,
Journal of medicinal chemistry,
Bin Pan, and
Renzheng Huang, and
Likang Zheng, and
Chen Chen, and
Shiqing Han, and
Di Qu, and
Mingli Zhu, and
Ping Wei
May 2012,
Bioorganic & medicinal chemistry,
Bin Pan, and
Renzheng Huang, and
Likang Zheng, and
Chen Chen, and
Shiqing Han, and
Di Qu, and
Mingli Zhu, and
Ping Wei
May 2012,
Bioorganic & medicinal chemistry letters,
Bin Pan, and
Renzheng Huang, and
Likang Zheng, and
Chen Chen, and
Shiqing Han, and
Di Qu, and
Mingli Zhu, and
Ping Wei
August 2021,
Bioorganic chemistry,
Bin Pan, and
Renzheng Huang, and
Likang Zheng, and
Chen Chen, and
Shiqing Han, and
Di Qu, and
Mingli Zhu, and
Ping Wei
May 2014,
Bioorganic & medicinal chemistry letters,
Bin Pan, and
Renzheng Huang, and
Likang Zheng, and
Chen Chen, and
Shiqing Han, and
Di Qu, and
Mingli Zhu, and
Ping Wei
January 2015,
European journal of medicinal chemistry,
Bin Pan, and
Renzheng Huang, and
Likang Zheng, and
Chen Chen, and
Shiqing Han, and
Di Qu, and
Mingli Zhu, and
Ping Wei
May 2012,
Bioorganic & medicinal chemistry,
Bin Pan, and
Renzheng Huang, and
Likang Zheng, and
Chen Chen, and
Shiqing Han, and
Di Qu, and
Mingli Zhu, and
Ping Wei
July 2020,
Advanced pharmaceutical bulletin,
Bin Pan, and
Renzheng Huang, and
Likang Zheng, and
Chen Chen, and
Shiqing Han, and
Di Qu, and
Mingli Zhu, and
Ping Wei
February 2024,
RSC advances,
