BIOMAT Database Logo BIOMAT Database Logo

Influence of thyrotropin-releasing hormone on autonomic nervous system determined by the variations in R-R interval on electrocardiogram. 1990

A Iwashita, and I Kobayashi, and T Inukai, and M Takahashi, and A Ishii, and K Ohshima, and M Mori, and Y Shimomura, and S Kobayashi
First Department of Internal Medicine, Gunma University School of Medicine, Maebashi, Japan.

The change of variation in R-R interval on electrocardiograms (CVq) was examined in healthy subjects and patients with Graves' disease before and after an intravenous administration of 500 micrograms of Thyrotropin-releasing hormone (TRH). CVq was significantly elevated after TRH stimulation and returned to the control level within 120 min. This phenomenon was found not only in healthy subjects but also in patients with untreated Graves' disease whose levels of CVq were lower than in normal subjects. Pretreatment with atropine inhibited the response of CVq to TRH. These data suggest that TRH has a stimulatory effect on the parasympathetic nervous system, determined by the variations in R-R interval.

UI MeSH Term Description Entries
D010890 Pirenzepine An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients. Gastrotsepin,Gastrozepin,L-S 519,LS-519,Piren-Basan,Pirenzepin,Pirenzepin Von Ct,Pirenzepin-Ratiopharm,Pirenzepine Dihydrochloride,Pyrenzepine,Ulcoprotect,Ulgescum,Dihydrochloride, Pirenzepine,LS 519,LS519,Piren Basan,Pirenzepin Ratiopharm,Von Ct, Pirenzepin
D011412 Propanolamines AMINO ALCOHOLS containing the propanolamine (NH2CH2CHOHCH2) group and its derivatives. Aminopropanols
D002395 Catecholamines A general class of ortho-dihydroxyphenylalkylamines derived from TYROSINE. Catecholamine,Sympathin,Sympathins
D004562 Electrocardiography Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY. 12-Lead ECG,12-Lead EKG,12-Lead Electrocardiography,Cardiography,ECG,EKG,Electrocardiogram,Electrocardiograph,12 Lead ECG,12 Lead EKG,12 Lead Electrocardiography,12-Lead ECGs,12-Lead EKGs,12-Lead Electrocardiographies,Cardiographies,ECG, 12-Lead,EKG, 12-Lead,Electrocardiograms,Electrocardiographies, 12-Lead,Electrocardiographs,Electrocardiography, 12-Lead
D006111 Graves Disease A common form of hyperthyroidism with a diffuse hyperplastic GOITER. It is an autoimmune disorder that produces antibodies against the THYROID STIMULATING HORMONE RECEPTOR. These autoantibodies activate the TSH receptor, thereby stimulating the THYROID GLAND and hypersecretion of THYROID HORMONES. These autoantibodies can also affect the eyes (GRAVES OPHTHALMOPATHY) and the skin (Graves dermopathy). Basedow's Disease,Exophthalmic Goiter,Goiter, Exophthalmic,Graves' Disease,Basedow Disease,Hyperthyroidism, Autoimmune,Basedows Disease,Disease, Basedow,Disease, Basedow's,Disease, Graves,Disease, Graves',Exophthalmic Goiters,Goiters, Exophthalmic
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000996 Antitussive Agents Agents that suppress cough. They act centrally on the medullary cough center. EXPECTORANTS, also used in the treatment of cough, act locally. Antitussive,Antitussive Agent,Antitussive Drug,Cough Suppressant,Antitussive Drugs,Antitussives,Cough Suppressants,Agent, Antitussive,Agents, Antitussive,Drug, Antitussive,Drugs, Antitussive,Suppressant, Cough,Suppressants, Cough
D001285 Atropine An alkaloid, originally from Atropa belladonna, but found in other plants, mainly SOLANACEAE. Hyoscyamine is the 3(S)-endo isomer of atropine. AtroPen,Atropin Augenöl,Atropine Sulfate,Atropine Sulfate Anhydrous,Atropinol,Anhydrous, Atropine Sulfate,Augenöl, Atropin,Sulfate Anhydrous, Atropine,Sulfate, Atropine
D001341 Autonomic Nervous System The ENTERIC NERVOUS SYSTEM; PARASYMPATHETIC NERVOUS SYSTEM; and SYMPATHETIC NERVOUS SYSTEM taken together. Generally speaking, the autonomic nervous system regulates the internal environment during both peaceful activity and physical or emotional stress. Autonomic activity is controlled and integrated by the CENTRAL NERVOUS SYSTEM, especially the HYPOTHALAMUS and the SOLITARY NUCLEUS, which receive information relayed from VISCERAL AFFERENTS. Vegetative Nervous System,Visceral Nervous System,Autonomic Nervous Systems,Nervous System, Autonomic,Nervous System, Vegetative,Nervous System, Visceral,Nervous Systems, Autonomic,Nervous Systems, Vegetative,Nervous Systems, Visceral,System, Autonomic Nervous,System, Vegetative Nervous,System, Visceral Nervous,Systems, Autonomic Nervous,Systems, Vegetative Nervous,Systems, Visceral Nervous,Vegetative Nervous Systems,Visceral Nervous Systems

Related Publications

A Iwashita, and I Kobayashi, and T Inukai, and M Takahashi, and A Ishii, and K Ohshima, and M Mori, and Y Shimomura, and S Kobayashi
[R-R interval variations and autonomic nervous function under general anesthesia].
February 1985, Masui. The Japanese journal of anesthesiology,
A Iwashita, and I Kobayashi, and T Inukai, and M Takahashi, and A Ishii, and K Ohshima, and M Mori, and Y Shimomura, and S Kobayashi
Thyrotropin-releasing hormone in lamprey central nervous system.
July 1985, Brain research,
A Iwashita, and I Kobayashi, and T Inukai, and M Takahashi, and A Ishii, and K Ohshima, and M Mori, and Y Shimomura, and S Kobayashi
Thyrotropin-releasing hormone and central nervous system trauma.
January 1989, Annals of the New York Academy of Sciences,
A Iwashita, and I Kobayashi, and T Inukai, and M Takahashi, and A Ishii, and K Ohshima, and M Mori, and Y Shimomura, and S Kobayashi
Influence of autonomic nervous activity on variations in the R-R intervals in adult goats.
June 1989, Nihon juigaku zasshi. The Japanese journal of veterinary science,
A Iwashita, and I Kobayashi, and T Inukai, and M Takahashi, and A Ishii, and K Ohshima, and M Mori, and Y Shimomura, and S Kobayashi
Gonadotropin-releasing hormone and thyrotropin-releasing hormone: distribution and effects in the central nervous system.
January 1976, Recent progress in hormone research,
A Iwashita, and I Kobayashi, and T Inukai, and M Takahashi, and A Ishii, and K Ohshima, and M Mori, and Y Shimomura, and S Kobayashi
Thyrotropin releasing factor: a putative CNS regulator of the autonomic nervous system.
January 1981, Life sciences,
A Iwashita, and I Kobayashi, and T Inukai, and M Takahashi, and A Ishii, and K Ohshima, and M Mori, and Y Shimomura, and S Kobayashi
[Role of the autonomic nervous system in the pathogenesis of vasospastic angina--neurogenic humoral regulators and ECG R-R interval variations].
November 1984, Kokyu to junkan. Respiration & circulation,
A Iwashita, and I Kobayashi, and T Inukai, and M Takahashi, and A Ishii, and K Ohshima, and M Mori, and Y Shimomura, and S Kobayashi
Thyrotropin-releasing hormone effects in the central nervous system: dependence on arousal state.
November 1981, Science (New York, N.Y.),
A Iwashita, and I Kobayashi, and T Inukai, and M Takahashi, and A Ishii, and K Ohshima, and M Mori, and Y Shimomura, and S Kobayashi
Evaluation of autonomic nervous activity in patients with vibration disease using electrocardiographic R-R interval variations.
January 1987, Industrial health,
A Iwashita, and I Kobayashi, and T Inukai, and M Takahashi, and A Ishii, and K Ohshima, and M Mori, and Y Shimomura, and S Kobayashi
Influence of the autonomic nervous system on the Q-T interval in man.
November 1982, The American journal of cardiology,
Copied contents to your clipboard!