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To define the prevalence of non-A, non-B hepatitis, antibodies to HCV were detected in 193 patients on renal replacement therapy (52 transplant and 141 hemodialysis patients) and in 50 staff members of a Nephrology Department. Unequivocal seroconversion was documented in 5 transplant (9.6%) and in 26 dialysis patients (18.4%). In the dialysis population, the prevalence of anti-HCV antibodies was evaluated in patients grouped according to the number of blood transfusions and to the different sections of dialytic treatment. The most striking findings were the marked differences in the prevalence of anti-HCV antibodies among patients treated in different sections (from 0% to 70%), and the presence of a significant increase in alanine-amino-transferase (ALT) concentrations in 14 anti-HCV negative patients. The results suggest that the diffusion of non-A, non-B hepatitis is mainly transfusion-related, with the possibility of significant environmental diffusion related to the violation of infection-control measures. The current immunoassay is probably unable to detect the actual frequency of the infection.
P Gilli, and
M Moretti, and
S Soffritti, and
N Marchi, and
F Malacarne, and
P L Bedani, and
E De Paoli Vitali, and
O Fiocchi, and
C Menini
January 1992,
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association,
P Gilli, and
M Moretti, and
S Soffritti, and
N Marchi, and
F Malacarne, and
P L Bedani, and
E De Paoli Vitali, and
O Fiocchi, and
C Menini
October 1990,
Revue francaise de transfusion et d'hemobiologie : bulletin de la Societe nationale de transfusion sanguine,
P Gilli, and
M Moretti, and
S Soffritti, and
N Marchi, and
F Malacarne, and
P L Bedani, and
E De Paoli Vitali, and
O Fiocchi, and
C Menini
February 1990,
Schweizerische medizinische Wochenschrift,
P Gilli, and
M Moretti, and
S Soffritti, and
N Marchi, and
F Malacarne, and
P L Bedani, and
E De Paoli Vitali, and
O Fiocchi, and
C Menini
July 1992,
Orvosi hetilap,
P Gilli, and
M Moretti, and
S Soffritti, and
N Marchi, and
F Malacarne, and
P L Bedani, and
E De Paoli Vitali, and
O Fiocchi, and
C Menini
February 1992,
Schweizerische medizinische Wochenschrift,
P Gilli, and
M Moretti, and
S Soffritti, and
N Marchi, and
F Malacarne, and
P L Bedani, and
E De Paoli Vitali, and
O Fiocchi, and
C Menini
January 1991,
Vox sanguinis,
P Gilli, and
M Moretti, and
S Soffritti, and
N Marchi, and
F Malacarne, and
P L Bedani, and
E De Paoli Vitali, and
O Fiocchi, and
C Menini
January 1991,
Digestive diseases and sciences,
P Gilli, and
M Moretti, and
S Soffritti, and
N Marchi, and
F Malacarne, and
P L Bedani, and
E De Paoli Vitali, and
O Fiocchi, and
C Menini
February 1994,
JPMA. The Journal of the Pakistan Medical Association,
P Gilli, and
M Moretti, and
S Soffritti, and
N Marchi, and
F Malacarne, and
P L Bedani, and
E De Paoli Vitali, and
O Fiocchi, and
C Menini
April 1990,
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology,
P Gilli, and
M Moretti, and
S Soffritti, and
N Marchi, and
F Malacarne, and
P L Bedani, and
E De Paoli Vitali, and
O Fiocchi, and
C Menini
January 2000,
Voprosy virusologii,
